BDBM50265427 4-[7-(1-Cyclopropylmethylpiperidin-4-yl)-2-(4-fluorophenyl) imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-ylamine::CHEMBL525196

SMILES: Nc1nccc(n1)-c1c(nc2cc(ccn12)C1CCN(CC2CC2)CC1)-c1ccc(F)cc1

InChI Key: InChIKey=UWHHIPRAZDUCHP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50265427   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50265427 (4-[7-(1-Cyclopropylmethylpiperidin-4-yl)-2-(4-fluo...) Show SMILES Nc1nccc(n1)-c1c(nc2cc(ccn12)C1CCN(CC2CC2)CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C26H27FN6/c27-21-5-3-19(4-6-21)24-25(22-7-11-29-26(28)30-22)33-14-10-20(15-23(33)31-24)18-8-12-32(13-9-18)16-17-1-2-17/h3-7,10-11,14-15,17-18H,1-2,8-9,12-13,16H2,(H2,28,29,30)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0950	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase				Eur J Med Chem 43: 1123-51 (2008) Article DOI: 10.1016/j.ejmech.2007.09.013 BindingDB Entry DOI: 10.7270/Q28C9W1H
					More data for this Ligand-Target Pair