BDBM50265615 4-Amino-3-(5,6-dimethylbenzimidazol-2-yl)hydroquinolin-2-one::CHEMBL498206

SMILES: Cc1cc2nc([nH]c2cc1C)-c1c(N)c2ccccc2[nH]c1=O

InChI Key: InChIKey=RKESDYSOJBSAAE-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50265615   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50265615 (4-Amino-3-(5,6-dimethylbenzimidazol-2-yl)hydroquin...) Show SMILES Cc1cc2nc([nH]c2cc1C)-c1c(N)c2ccccc2[nH]c1=O Show InChI InChI=1S/C18H16N4O/c1-9-7-13-14(8-10(9)2)21-17(20-13)15-16(19)11-5-3-4-6-12(11)22-18(15)23/h3-8H,1-2H3,(H,20,21)(H3,19,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2				J Med Chem 52: 278-92 (2009) Article DOI: 10.1021/jm800790t BindingDB Entry DOI: 10.7270/Q2TD9X7X
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50265615 (4-Amino-3-(5,6-dimethylbenzimidazol-2-yl)hydroquin...) Show SMILES Cc1cc2nc([nH]c2cc1C)-c1c(N)c2ccccc2[nH]c1=O Show InChI InChI=1S/C18H16N4O/c1-9-7-13-14(8-10(9)2)21-17(20-13)15-16(19)11-5-3-4-6-12(11)22-18(15)23/h3-8H,1-2H3,(H,20,21)(H3,19,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of human recombinant PDGFRbeta				J Med Chem 52: 278-92 (2009) Article DOI: 10.1021/jm800790t BindingDB Entry DOI: 10.7270/Q2TD9X7X
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50265615 (4-Amino-3-(5,6-dimethylbenzimidazol-2-yl)hydroquin...) Show SMILES Cc1cc2nc([nH]c2cc1C)-c1c(N)c2ccccc2[nH]c1=O Show InChI InChI=1S/C18H16N4O/c1-9-7-13-14(8-10(9)2)21-17(20-13)15-16(19)11-5-3-4-6-12(11)22-18(15)23/h3-8H,1-2H3,(H,20,21)(H3,19,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of human recombinant FGFR1				J Med Chem 52: 278-92 (2009) Article DOI: 10.1021/jm800790t BindingDB Entry DOI: 10.7270/Q2TD9X7X
					More data for this Ligand-Target Pair