BDBM50265867 7-Fluoro-5-[4-(4-isopropyl-piperazin-1-yl)-2-methoxy-phenylamino]-3H-3,4,5a,11-tetraaza-cyclopenta[a]anthracen-6-one::CHEMBL457322

SMILES: COc1cc(ccc1Nc1nc2[nH]ccc2c2nc3cccc(F)c3c(=O)n12)N1CCN(CC1)C(C)C

InChI Key: InChIKey=XUWNJSIFMUTIRM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50265867   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor I receptor (Homo sapiens (Human))	BDBM50265867 (7-Fluoro-5-[4-(4-isopropyl-piperazin-1-yl)-2-metho...) Show SMILES COc1cc(ccc1Nc1nc2[nH]ccc2c2nc3cccc(F)c3c(=O)n12)N1CCN(CC1)C(C)C Show InChI InChI=1S/C27H28FN7O2/c1-16(2)33-11-13-34(14-12-33)17-7-8-20(22(15-17)37-3)31-27-32-24-18(9-10-29-24)25-30-21-6-4-5-19(28)23(21)26(36)35(25)27/h4-10,15-16,29H,11-14H2,1-3H3,(H,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of IGF1R				Bioorg Med Chem Lett 19: 373-7 (2008) Article DOI: 10.1016/j.bmcl.2008.11.065 BindingDB Entry DOI: 10.7270/Q2F190PC
					More data for this Ligand-Target Pair
Insulin-like growth factor I receptor (Homo sapiens (Human))	BDBM50265867 (7-Fluoro-5-[4-(4-isopropyl-piperazin-1-yl)-2-metho...) Show SMILES COc1cc(ccc1Nc1nc2[nH]ccc2c2nc3cccc(F)c3c(=O)n12)N1CCN(CC1)C(C)C Show InChI InChI=1S/C27H28FN7O2/c1-16(2)33-11-13-34(14-12-33)17-7-8-20(22(15-17)37-3)31-27-32-24-18(9-10-29-24)25-30-21-6-4-5-19(28)23(21)26(36)35(25)27/h4-10,15-16,29H,11-14H2,1-3H3,(H,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of IGF1R phosphorylation by cellular assay				Bioorg Med Chem Lett 19: 373-7 (2008) Article DOI: 10.1016/j.bmcl.2008.11.065 BindingDB Entry DOI: 10.7270/Q2F190PC
					More data for this Ligand-Target Pair