BDBM50265917 4-((4-tert-butylphenyl)ethynyl)benzoic acid::CHEMBL457775
SMILES: CC(C)(C)c1ccc(cc1)C#Cc1ccc(cc1)C(O)=O
InChI Key: InChIKey=ODGSTXCQFQIDED-UHFFFAOYSA-N
Data: 3 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Retinoid X receptor gamma/retinoic acid receptor alpha (Homo sapiens (Human)) | BDBM50265917 (4-((4-tert-butylphenyl)ethynyl)benzoic acid | CHEM...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Activity at human RARalpha ligand binding domain expressed in COS7 cells cotransfected with Gal4-DBD assessed as transcriptional activation after 16 ... | Bioorg Med Chem Lett 19: 489-92 (2008) Article DOI: 10.1016/j.bmcl.2008.11.040 BindingDB Entry DOI: 10.7270/Q2GF0TC9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoid receptor (Homo sapiens (Human)) | BDBM50265917 (4-((4-tert-butylphenyl)ethynyl)benzoic acid | CHEM...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Activity at human RARgamma ligand binding domain expressed in COS7 cells cotransfected with Gal4-DBD assessed as transcriptional activation after 16 ... | Bioorg Med Chem Lett 19: 489-92 (2008) Article DOI: 10.1016/j.bmcl.2008.11.040 BindingDB Entry DOI: 10.7270/Q2GF0TC9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Retinoid receptor (Homo sapiens (Human)) | BDBM50265917 (4-((4-tert-butylphenyl)ethynyl)benzoic acid | CHEM...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Activity at human RARbeta ligand binding domain expressed in COS7 cells cotransfected with Gal4-DBD assessed as transcriptional activation after 16 h... | Bioorg Med Chem Lett 19: 489-92 (2008) Article DOI: 10.1016/j.bmcl.2008.11.040 BindingDB Entry DOI: 10.7270/Q2GF0TC9 | |||||||||||
More data for this Ligand-Target Pair |