Found 3 hits for monomerid = 50265928 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50265928
(CHEMBL4086641)Show SMILES [H][C@@]12CC[C@@]3(C)[C@@H](CC(=O)C(O)=C3[C@@]1(C)C[C@H](OC2=O)c1ccoc1)C(=O)OC |r,c:11| Show InChI InChI=1S/C21H24O7/c1-20-6-4-12-19(25)28-15(11-5-7-27-10-11)9-21(12,2)17(20)16(23)14(22)8-13(20)18(24)26-3/h5,7,10,12-13,15,23H,4,6,8-9H2,1-3H3/t12-,13-,15-,20-,21-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
The University of Kansas
Curated by ChEMBL
| Assay Description Agonist activity at human kappa-type opioid receptor expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation after 30 mins in prese... |
J Med Chem 60: 3866-3878 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00148 BindingDB Entry DOI: 10.7270/Q2K93B08 |
More data for this Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50265928
(CHEMBL4086641)Show SMILES [H][C@@]12CC[C@@]3(C)[C@@H](CC(=O)C(O)=C3[C@@]1(C)C[C@H](OC2=O)c1ccoc1)C(=O)OC |r,c:11| Show InChI InChI=1S/C21H24O7/c1-20-6-4-12-19(25)28-15(11-5-7-27-10-11)9-21(12,2)17(20)16(23)14(22)8-13(20)18(24)26-3/h5,7,10,12-13,15,23H,4,6,8-9H2,1-3H3/t12-,13-,15-,20-,21-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50265928
(CHEMBL4086641)Show SMILES [H][C@@]12CC[C@@]3(C)[C@@H](CC(=O)C(O)=C3[C@@]1(C)C[C@H](OC2=O)c1ccoc1)C(=O)OC |r,c:11| Show InChI InChI=1S/C21H24O7/c1-20-6-4-12-19(25)28-15(11-5-7-27-10-11)9-21(12,2)17(20)16(23)14(22)8-13(20)18(24)26-3/h5,7,10,12-13,15,23H,4,6,8-9H2,1-3H3/t12-,13-,15-,20-,21-/m0/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |