BDBM50266110 (R)-3-(4-(dimethylamino)benzylthio)-2-(4-mercaptobutanamido)propanoic acid::CHEMBL445489

SMILES: CN(C)c1ccc(CSC[C@H](NC(=O)CCCS)C(O)=O)cc1

InChI Key: InChIKey=MOPOLVGSVDGSQU-AWEZNQCLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50266110   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Cavia porcellus)	BDBM50266110 ((R)-3-(4-(dimethylamino)benzylthio)-2-(4-mercaptob...) Show SMILES CN(C)c1ccc(CSC[C@H](NC(=O)CCCS)C(O)=O)cc1 |r| Show InChI InChI=1S/C16H24N2O3S2/c1-18(2)13-7-5-12(6-8-13)10-23-11-14(16(20)21)17-15(19)4-3-9-22/h5-8,14,22H,3-4,9-11H2,1-2H3,(H,17,19)(H,20,21)/t14-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Santen Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 production				Bioorg Med Chem Lett 19: 442-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.042 BindingDB Entry DOI: 10.7270/Q20K28FC
					More data for this Ligand-Target Pair