BDBM50266236 (S)-2-(4-fluoro-3-(trifluoromethyl)phenyl)-N-(2-oxotetrahydrofuran-3-yl)acetamide::CHEMBL511677

SMILES: Fc1ccc(CC(=O)N[C@H]2CCOC2=O)cc1C(F)(F)F

InChI Key: InChIKey=UXKGQLOVTJTXOI-JTQLQIEISA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50266236   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcriptional activator protein luxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50266236 ((S)-2-(4-fluoro-3-(trifluoromethyl)phenyl)-N-(2-ox...) Show SMILES Fc1ccc(CC(=O)N[C@H]2CCOC2=O)cc1C(F)(F)F |r| Show InChI InChI=1S/C13H11F4NO3/c14-9-2-1-7(5-8(9)13(15,16)17)6-11(19)18-10-3-4-21-12(10)20/h1-2,5,10H,3-4,6H2,(H,18,19)/t10-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair