BDBM50266266 (S)-2-(naphthalen-1-yl)-N-(2-oxotetrahydrofuran-3-yl)acetamide::CHEMBL508553

SMILES: O=C(Cc1cccc2ccccc12)N[C@H]1CCOC1=O

InChI Key: InChIKey=QPFQOAWLJNWAEP-AWEZNQCLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50266266   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcriptional activator protein luxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50266266 ((S)-2-(naphthalen-1-yl)-N-(2-oxotetrahydrofuran-3-...) Show SMILES O=C(Cc1cccc2ccccc12)N[C@H]1CCOC1=O |r| Show InChI InChI=1S/C16H15NO3/c18-15(17-14-8-9-20-16(14)19)10-12-6-3-5-11-4-1-2-7-13(11)12/h1-7,14H,8-10H2,(H,17,18)/t14-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair