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SMILES: CN1CCN(CC1)c1cnc2cc(F)cc(-c3ccccc3)c2n1

InChI Key: InChIKey=AOOSUCZLZQJURM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50266290   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50266290 (6-fluoro-2-(4-methylpiperazin-1-yl)-8-phenylquinox...) Show SMILES CN1CCN(CC1)c1cnc2cc(F)cc(-c3ccccc3)c2n1 Show InChI InChI=1S/C19H19FN4/c1-23-7-9-24(10-8-23)18-13-21-17-12-15(20)11-16(19(17)22-18)14-5-3-2-4-6-14/h2-6,11-13H,7-10H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of human c-MET				Eur J Med Chem 46: 3675-80 (2011) Article DOI: 10.1016/j.ejmech.2011.05.031 BindingDB Entry DOI: 10.7270/Q2891676
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50266290 (6-fluoro-2-(4-methylpiperazin-1-yl)-8-phenylquinox...) Show SMILES CN1CCN(CC1)c1cnc2cc(F)cc(-c3ccccc3)c2n1 Show InChI InChI=1S/C19H19FN4/c1-23-7-9-24(10-8-23)18-13-21-17-12-15(20)11-16(19(17)22-18)14-5-3-2-4-6-14/h2-6,11-13H,7-10H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
UCB Celltech Curated by ChEMBL					Assay Description Inhibition of human recombinant his-tagged c-Met by TR-FRET assay				Bioorg Med Chem Lett 19: 397-400 (2008) Article DOI: 10.1016/j.bmcl.2008.11.062 BindingDB Entry DOI: 10.7270/Q2ZC82QC
					More data for this Ligand-Target Pair