BDBM50266687 CHEMBL4072029

SMILES: CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O

InChI Key: InChIKey=HIALMOPETFJDKR-VZWAHKEYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50266687   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon-like peptide 1 receptor (Homo sapiens (Human))	BDBM50266687 (CHEMBL4072029) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O |r| Show InChI InChI=1S/C195H308N58O60S2/c1-18-98(10)152(186(307)232-121(56-62-149(273)274)169(290)237-129(80-106-85-214-110-42-26-25-41-108(106)110)175(296)234-124(75-94(2)3)172(293)229-123(64-74-315-17)171(292)239-131(83-143(202)264)180(301)250-154(102(14)259)188(309)231-113(44-28-30-66-197)163(284)221-114(46-32-68-212-194(206)207)164(285)238-130(82-142(201)263)176(297)220-111(45-31-67-211-193(204)205)159(280)215-87-144(265)218-100(12)190(311)252-71-35-49-138(252)192(313)253-72-36-50-139(253)191(312)251-70-34-48-137(251)184(305)242-133(89-254)156(203)277)248-178(299)127(78-104-37-21-19-22-38-104)236-173(294)125(76-95(4)5)233-165(286)115(47-33-69-213-195(208)209)230-185(306)151(97(8)9)247-157(278)99(11)219-161(282)118(53-59-146(267)268)225-167(288)119(54-60-147(269)270)226-168(289)120(55-61-148(271)272)227-170(291)122(63-73-314-16)228-166(287)117(52-58-141(200)262)224-162(283)112(43-27-29-65-196)222-182(303)135(91-256)244-174(295)126(77-96(6)7)235-177(298)132(84-150(275)276)240-183(304)136(92-257)245-189(310)155(103(15)260)249-179(300)128(79-105-39-23-20-24-40-105)241-187(308)153(101(13)258)246-145(266)88-216-160(281)116(51-57-140(199)261)223-181(302)134(90-255)243-158(279)109(198)81-107-86-210-93-217-107/h19-26,37-42,85-86,93-103,109,111-139,151-155,214,254-260H,18,27-36,43-84,87-92,196-198H2,1-17H3,(H2,199,261)(H2,200,262)(H2,201,263)(H2,202,264)(H2,203,277)(H,210,217)(H,215,280)(H,216,281)(H,218,265)(H,219,282)(H,220,297)(H,221,284)(H,222,303)(H,223,302)(H,224,283)(H,225,288)(H,226,289)(H,227,291)(H,228,287)(H,229,293)(H,230,306)(H,231,309)(H,232,307)(H,233,286)(H,234,296)(H,235,298)(H,236,294)(H,237,290)(H,238,285)(H,239,292)(H,240,304)(H,241,308)(H,242,305)(H,243,279)(H,244,295)(H,245,310)(H,246,266)(H,247,278)(H,248,299)(H,249,300)(H,250,301)(H,267,268)(H,269,270)(H,271,272)(H,273,274)(H,275,276)(H4,204,205,211)(H4,206,207,212)(H4,208,209,213)/t98-,99-,100-,101+,102+,103+,109-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,151-,152-,153-,154-,155-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.20	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Agonist activity at human GLP-1 receptor expressed in HEK293 cells assessed as cAMP accumulation after 30 mins by HTRF assay				J Med Chem 60: 4293-4303 (2017) Article DOI: 10.1021/acs.jmedchem.7b00174 BindingDB Entry DOI: 10.7270/Q27S7R7M
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50266687 (CHEMBL4072029) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O |r| Show InChI InChI=1S/C195H308N58O60S2/c1-18-98(10)152(186(307)232-121(56-62-149(273)274)169(290)237-129(80-106-85-214-110-42-26-25-41-108(106)110)175(296)234-124(75-94(2)3)172(293)229-123(64-74-315-17)171(292)239-131(83-143(202)264)180(301)250-154(102(14)259)188(309)231-113(44-28-30-66-197)163(284)221-114(46-32-68-212-194(206)207)164(285)238-130(82-142(201)263)176(297)220-111(45-31-67-211-193(204)205)159(280)215-87-144(265)218-100(12)190(311)252-71-35-49-138(252)192(313)253-72-36-50-139(253)191(312)251-70-34-48-137(251)184(305)242-133(89-254)156(203)277)248-178(299)127(78-104-37-21-19-22-38-104)236-173(294)125(76-95(4)5)233-165(286)115(47-33-69-213-195(208)209)230-185(306)151(97(8)9)247-157(278)99(11)219-161(282)118(53-59-146(267)268)225-167(288)119(54-60-147(269)270)226-168(289)120(55-61-148(271)272)227-170(291)122(63-73-314-16)228-166(287)117(52-58-141(200)262)224-162(283)112(43-27-29-65-196)222-182(303)135(91-256)244-174(295)126(77-96(6)7)235-177(298)132(84-150(275)276)240-183(304)136(92-257)245-189(310)155(103(15)260)249-179(300)128(79-105-39-23-20-24-40-105)241-187(308)153(101(13)258)246-145(266)88-216-160(281)116(51-57-140(199)261)223-181(302)134(90-255)243-158(279)109(198)81-107-86-210-93-217-107/h19-26,37-42,85-86,93-103,109,111-139,151-155,214,254-260H,18,27-36,43-84,87-92,196-198H2,1-17H3,(H2,199,261)(H2,200,262)(H2,201,263)(H2,202,264)(H2,203,277)(H,210,217)(H,215,280)(H,216,281)(H,218,265)(H,219,282)(H,220,297)(H,221,284)(H,222,303)(H,223,302)(H,224,283)(H,225,288)(H,226,289)(H,227,291)(H,228,287)(H,229,293)(H,230,306)(H,231,309)(H,232,307)(H,233,286)(H,234,296)(H,235,298)(H,236,294)(H,237,290)(H,238,285)(H,239,292)(H,240,304)(H,241,308)(H,242,305)(H,243,279)(H,244,295)(H,245,310)(H,246,266)(H,247,278)(H,248,299)(H,249,300)(H,250,301)(H,267,268)(H,269,270)(H,271,272)(H,273,274)(H,275,276)(H4,204,205,211)(H4,206,207,212)(H4,208,209,213)/t98-,99-,100-,101+,102+,103+,109-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,151-,152-,153-,154-,155-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.24E+3	n/a	n/a	n/a	n/a
Sanofi-Aventis Deutschland GmbH Curated by ChEMBL					Assay Description Agonist activity at human glucagon receptor expressed in HEK293 cells assessed as cAMP accumulation after 30 mins by HTRF assay				J Med Chem 60: 4293-4303 (2017) Article DOI: 10.1021/acs.jmedchem.7b00174 BindingDB Entry DOI: 10.7270/Q27S7R7M
					More data for this Ligand-Target Pair