BDBM50266788 CHEMBL4067192

SMILES: Cl.NCc1ccnc(Oc2cccc(c2)C(=O)NCc2ccccc2)c1

InChI Key: InChIKey=FQVUWJYJPDWXIX-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50266788   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysyl oxidase (Homo sapiens (Human))	BDBM50266788 (CHEMBL4067192) Show SMILES Cl.NCc1ccnc(Oc2cccc(c2)C(=O)NCc2ccccc2)c1 Show InChI InChI=1S/C20H19N3O2/c21-13-16-9-10-22-19(11-16)25-18-8-4-7-17(12-18)20(24)23-14-15-5-2-1-3-6-15/h1-12H,13-14,21H2,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
PharmAkea Therapeutics Curated by ChEMBL					Assay Description Inhibition of human LOX expressed in HEK cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs foll...				J Med Chem 60: 4403-4423 (2017) Article DOI: 10.1021/acs.jmedchem.7b00345 BindingDB Entry DOI: 10.7270/Q2QV3Q0K
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50266788 (CHEMBL4067192) Show SMILES Cl.NCc1ccnc(Oc2cccc(c2)C(=O)NCc2ccccc2)c1 Show InChI InChI=1S/C20H19N3O2/c21-13-16-9-10-22-19(11-16)25-18-8-4-7-17(12-18)20(24)23-14-15-5-2-1-3-6-15/h1-12H,13-14,21H2,(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
PharmAkea Therapeutics Curated by ChEMBL					Assay Description Inhibition of recombinant human LOXL2 expressed in human whole blood assessed as reduction of H2O2 production from oxidative deamination of DAP prein...				J Med Chem 60: 4403-4423 (2017) Article DOI: 10.1021/acs.jmedchem.7b00345 BindingDB Entry DOI: 10.7270/Q2QV3Q0K
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50266788 (CHEMBL4067192) Show SMILES Cl.NCc1ccnc(Oc2cccc(c2)C(=O)NCc2ccccc2)c1 Show InChI InChI=1S/C20H19N3O2/c21-13-16-9-10-22-19(11-16)25-18-8-4-7-17(12-18)20(24)23-14-15-5-2-1-3-6-15/h1-12H,13-14,21H2,(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
PharmAkea Therapeutics Curated by ChEMBL					Assay Description Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...				J Med Chem 60: 4403-4423 (2017) Article DOI: 10.1021/acs.jmedchem.7b00345 BindingDB Entry DOI: 10.7270/Q2QV3Q0K
					More data for this Ligand-Target Pair
Lysyl oxidase homolog 2 (Homo sapiens (Human))	BDBM50266788 (CHEMBL4067192) Show SMILES Cl.NCc1ccnc(Oc2cccc(c2)C(=O)NCc2ccccc2)c1 Show InChI InChI=1S/C20H19N3O2/c21-13-16-9-10-22-19(11-16)25-18-8-4-7-17(12-18)20(24)23-14-15-5-2-1-3-6-15/h1-12H,13-14,21H2,(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
PharmAkea Therapeutics Curated by ChEMBL					Assay Description Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...				J Med Chem 60: 4403-4423 (2017) Article DOI: 10.1021/acs.jmedchem.7b00345 BindingDB Entry DOI: 10.7270/Q2QV3Q0K
					More data for this Ligand-Target Pair