BDBM50266936 CHEMBL4078601
SMILES: OB(O)c1cccc(CCN2CCN(CC2)c2nc(O)c(Cc3ccc(Cl)c(Cl)c3)s2)c1
InChI Key: InChIKey=ALEYRKKETTZIRR-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Mus musculus) | BDBM50266936 (CHEMBL4078601) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda California, Inc. Curated by ChEMBL | Assay Description Inhibition of mouse ATX using TG-mTMP as substrate after 2 hrs by fluorometric analysis | J Med Chem 60: 5209-5215 (2017) Article DOI: 10.1021/acs.jmedchem.6b01224 BindingDB Entry DOI: 10.7270/Q2319ZCT | |||||||||||
More data for this Ligand-Target Pair |