null

SMILES: Cc1ccc(Oc2ccc(cc2)N2CCC[C@H]2CC(O)=O)cc1

InChI Key: InChIKey=YGNWANUNGJNBAM-INIZCTEOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267018   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 1 (Mus musculus)	BDBM50267018 (CHEMBL4065518) Show SMILES Cc1ccc(Oc2ccc(cc2)N2CCC[C@H]2CC(O)=O)cc1 |r| Show InChI InChI=1S/C19H21NO3/c1-14-4-8-17(9-5-14)23-18-10-6-15(7-11-18)20-12-2-3-16(20)13-19(21)22/h4-11,16H,2-3,12-13H2,1H3,(H,21,22)/t16-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at GPR40 in mouse STC1 cells assessed as induction of GLP-1 secretion measured after 1 hr by HTRF assay				J Med Chem 60: 1417-1431 (2017) Article DOI: 10.1021/acs.jmedchem.6b01559 BindingDB Entry DOI: 10.7270/Q25X2CD5
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50267018 (CHEMBL4065518) Show SMILES Cc1ccc(Oc2ccc(cc2)N2CCC[C@H]2CC(O)=O)cc1 |r| Show InChI InChI=1S/C19H21NO3/c1-14-4-8-17(9-5-14)23-18-10-6-15(7-11-18)20-12-2-3-16(20)13-19(21)22/h4-11,16H,2-3,12-13H2,1H3,(H,21,22)/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	490	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assay				J Med Chem 60: 1417-1431 (2017) Article DOI: 10.1021/acs.jmedchem.6b01559 BindingDB Entry DOI: 10.7270/Q25X2CD5
					More data for this Ligand-Target Pair