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BDBM50267024 1-(2-(1H-indol-3-yl)ethyl)-4-acetyl-5-(4-ethoxyphenyl)-3-hydroxy-1H-pyrrol-2(5H)-one::BAS-8770951::CHEMBL478323

SMILES: CCOc1ccc(cc1)C1C(C(C)=O)C(=O)C(=O)N1CCc1c[nH]c2ccccc12

InChI Key: InChIKey=AOCQGIPYGLNRLR-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50267024   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase pim-1


(Homo sapiens (Human))
BDBM50267024
PNG
(1-(2-(1H-indol-3-yl)ethyl)-4-acetyl-5-(4-ethoxyphe...)
Show SMILES CCOc1ccc(cc1)C1C(C(C)=O)C(=O)C(=O)N1CCc1c[nH]c2ccccc12
Show InChI InChI=1S/C24H24N2O4/c1-3-30-18-10-8-16(9-11-18)22-21(15(2)27)23(28)24(29)26(22)13-12-17-14-25-20-7-5-4-6-19(17)20/h4-11,14,21-22,25H,3,12-13H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
4.20E+3n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Inhibition of human recombinant Pim1 expressed in insect cells by HTRF


Bioorg Med Chem Lett 19: 1512-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.005
BindingDB Entry DOI: 10.7270/Q2RF5VX8
More data for this
Ligand-Target Pair