BDBM50267070 4-{[5-(3-Benzyloxybenzylidene)-4-oxo-2-phenyliminothiazolidin-3-yl]methyl}benzoic acid::CHEMBL514239

SMILES: OC(=O)c1ccc(CN2\C(S\C(=C/c3cccc(OCc4ccccc4)c3)C2=O)=N\c2ccccc2)cc1

InChI Key: InChIKey=MPQXUNZUKGEJKK-VFHDLGNDSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50267070   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50267070 (4-{[5-(3-Benzyloxybenzylidene)-4-oxo-2-phenylimino...) Show SMILES OC(=O)c1ccc(CN2\C(S\C(=C/c3cccc(OCc4ccccc4)c3)C2=O)=N\c2ccccc2)cc1 Show InChI InChI=1S/C31H24N2O4S/c34-29-28(19-24-10-7-13-27(18-24)37-21-23-8-3-1-4-9-23)38-31(32-26-11-5-2-6-12-26)33(29)20-22-14-16-25(17-15-22)30(35)36/h1-19H,20-21H2,(H,35,36)/b28-19-,32-31-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Messina Curated by ChEMBL					Assay Description Inhibition of GST-tagged human PTP1B				Bioorg Med Chem 17: 1928-37 (2009) Article DOI: 10.1016/j.bmc.2009.01.044 BindingDB Entry DOI: 10.7270/Q2FN162Z
					More data for this Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase (Saccharomyces cerevisiae)	BDBM50267070 (4-{[5-(3-Benzyloxybenzylidene)-4-oxo-2-phenylimino...) Show SMILES OC(=O)c1ccc(CN2\C(S\C(=C/c3cccc(OCc4ccccc4)c3)C2=O)=N\c2ccccc2)cc1 Show InChI InChI=1S/C31H24N2O4S/c34-29-28(19-24-10-7-13-27(18-24)37-21-23-8-3-1-4-9-23)38-31(32-26-11-5-2-6-12-26)33(29)20-22-14-16-25(17-15-22)30(35)36/h1-19H,20-21H2,(H,35,36)/b28-19-,32-31-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Messina Curated by ChEMBL					Assay Description Inhibition of Saccharomyces cerevisiae Ltp1				Bioorg Med Chem 17: 1928-37 (2009) Article DOI: 10.1016/j.bmc.2009.01.044 BindingDB Entry DOI: 10.7270/Q2FN162Z
					More data for this Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase (Homo sapiens (Human))	BDBM50267070 (4-{[5-(3-Benzyloxybenzylidene)-4-oxo-2-phenylimino...) Show SMILES OC(=O)c1ccc(CN2\C(S\C(=C/c3cccc(OCc4ccccc4)c3)C2=O)=N\c2ccccc2)cc1 Show InChI InChI=1S/C31H24N2O4S/c34-29-28(19-24-10-7-13-27(18-24)37-21-23-8-3-1-4-9-23)38-31(32-26-11-5-2-6-12-26)33(29)20-22-14-16-25(17-15-22)30(35)36/h1-19H,20-21H2,(H,35,36)/b28-19-,32-31-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Messina Curated by ChEMBL					Assay Description Inhibition of GST-tagged human LMW PTP1B IF1 isoform				Bioorg Med Chem 17: 1928-37 (2009) Article DOI: 10.1016/j.bmc.2009.01.044 BindingDB Entry DOI: 10.7270/Q2FN162Z
					More data for this Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase (Homo sapiens (Human))	BDBM50267070 (4-{[5-(3-Benzyloxybenzylidene)-4-oxo-2-phenylimino...) Show SMILES OC(=O)c1ccc(CN2\C(S\C(=C/c3cccc(OCc4ccccc4)c3)C2=O)=N\c2ccccc2)cc1 Show InChI InChI=1S/C31H24N2O4S/c34-29-28(19-24-10-7-13-27(18-24)37-21-23-8-3-1-4-9-23)38-31(32-26-11-5-2-6-12-26)33(29)20-22-14-16-25(17-15-22)30(35)36/h1-19H,20-21H2,(H,35,36)/b28-19-,32-31-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Messina Curated by ChEMBL					Assay Description Inhibition of GST-tagged human LMW PTP1B IF1 isoform				Bioorg Med Chem 17: 1928-37 (2009) Article DOI: 10.1016/j.bmc.2009.01.044 BindingDB Entry DOI: 10.7270/Q2FN162Z
					More data for this Ligand-Target Pair