BDBM50267090 2-(3-(9H-carbazol-9-yl)-2-hydroxypropoxy)benzaldehyde oxime::CHEMBL515778

SMILES: OC(COc1ccccc1CN=O)Cn1c2ccccc2c2ccccc12

InChI Key: InChIKey=ROCKFCNIHUESHH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50267090   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50267090 (2-(3-(9H-carbazol-9-yl)-2-hydroxypropoxy)benzaldeh...) Show SMILES OC(COc1ccccc1CN=O)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C22H20N2O3/c25-17(15-27-22-12-6-1-7-16(22)13-23-26)14-24-20-10-4-2-8-18(20)19-9-3-5-11-21(19)24/h1-12,17,25H,13-15H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human recombinant Pim1 expressed in insect cells by HTRF				Bioorg Med Chem Lett 19: 1512-6 (2009) Article DOI: 10.1016/j.bmcl.2009.01.005 BindingDB Entry DOI: 10.7270/Q2RF5VX8
					More data for this Ligand-Target Pair