BDBM50267091 BAS-1059623::CHEMBL476454::N-(2-(1H-indol-3-yl)ethyl)-4-chloro-N-(9-methyl-9-azabicyclo[4.2.1]non-2-en-3-yl)benzamide

SMILES: CN1C2CCC1C=C(CC2)N(CCc1c[nH]c2ccccc12)C(=O)c1ccc(Cl)cc1

InChI Key: InChIKey=XCKRXJPTOWBXKQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50267091   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50267091 (BAS-1059623 | CHEMBL476454 | N-(2-(1H-indol-3-yl)e...) Show SMILES CN1C2CCC1C=C(CC2)N(CCc1c[nH]c2ccccc12)C(=O)c1ccc(Cl)cc1 |c:7,THB:0:1:7.6.8.9:4.3| Show InChI InChI=1S/C26H28ClN3O/c1-29-21-10-12-22(29)16-23(13-11-21)30(26(31)18-6-8-20(27)9-7-18)15-14-19-17-28-25-5-3-2-4-24(19)25/h2-9,16-17,21-22,28H,10-15H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human recombinant Pim1 expressed in insect cells by HTRF				Bioorg Med Chem Lett 19: 1512-6 (2009) Article DOI: 10.1016/j.bmcl.2009.01.005 BindingDB Entry DOI: 10.7270/Q2RF5VX8
					More data for this Ligand-Target Pair