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SMILES: OC(CC1C[NH+]2CCC1CC2)(c1ccccc1)c1ccccc1

InChI Key: InChIKey=RBPCUBPNDXDMKG-UHFFFAOYSA-O

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50267392   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))		BDBM50267392
PNG
(2-(1-Azabicyclo[2.2.2]oct-3-yl)-1,1-diphenylethano...)
Show SMILES OC(CC1C[NH+]2CCC1CC2)(c1ccccc1)c1ccccc1 |(-5.84,-18.12,;-5.06,-19.46,;-6.4,-20.23,;-7.74,-19.46,;-7.74,-17.9,;-9.09,-17.12,;-10.42,-17.9,;-10.42,-19.46,;-9.09,-20.23,;-8.43,-18.93,;-9.72,-18.3,;-3.74,-18.68,;-2.39,-19.44,;-1.07,-18.65,;-1.08,-17.11,;-2.44,-16.36,;-3.76,-17.14,;-4.3,-20.79,;-5.08,-22.11,;-4.32,-23.44,;-2.79,-23.44,;-2.02,-22.11,;-2.78,-20.79,)|
Show InChI InChI=1S/C21H25NO/c23-21(19-7-3-1-4-8-19,20-9-5-2-6-10-20)15-18-16-22-13-11-17(18)12-14-22/h1-10,17-18,23H,11-16H2/p+1
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Article
PubMed
n/an/a 1.45E+5n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human cloned muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilizatio...

J Med Chem 52: 2493-505 (2009)


Article DOI: 10.1021/jm801601v
BindingDB Entry DOI: 10.7270/Q2H131X8
More data for this
Ligand-Target Pair