BDBM50267432 CHEMBL476466::N-(1-(2-Aminophenyl)-2,6-dioxopiperidin-3-yl)-3,4,5-trimethoxybenzamide

SMILES: COc1cc(cc(OC)c1OC)C(=O)NC1CCC(=O)N(C1=O)c1ccccc1N

InChI Key: InChIKey=BUQMNSXLQZDEDH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267432   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50267432 (CHEMBL476466 | N-(1-(2-Aminophenyl)-2,6-dioxopiper...) Show SMILES COc1cc(cc(OC)c1OC)C(=O)NC1CCC(=O)N(C1=O)c1ccccc1N Show InChI InChI=1S/C21H23N3O6/c1-28-16-10-12(11-17(29-2)19(16)30-3)20(26)23-14-8-9-18(25)24(21(14)27)15-7-5-4-6-13(15)22/h4-7,10-11,14H,8-9,22H2,1-3H3,(H,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of MMP2 by spectrophotometry				Bioorg Med Chem 17: 3053-60 (2009) Article DOI: 10.1016/j.bmc.2009.02.063 BindingDB Entry DOI: 10.7270/Q2NP25BQ
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50267432 (CHEMBL476466 | N-(1-(2-Aminophenyl)-2,6-dioxopiper...) Show SMILES COc1cc(cc(OC)c1OC)C(=O)NC1CCC(=O)N(C1=O)c1ccccc1N Show InChI InChI=1S/C21H23N3O6/c1-28-16-10-12(11-17(29-2)19(16)30-3)20(26)23-14-8-9-18(25)24(21(14)27)15-7-5-4-6-13(15)22/h4-7,10-11,14H,8-9,22H2,1-3H3,(H,23,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.04E+5	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of pig kidney microsome aminopeptidase N by UV-visible spectrophotometer				Bioorg Med Chem 17: 3053-60 (2009) Article DOI: 10.1016/j.bmc.2009.02.063 BindingDB Entry DOI: 10.7270/Q2NP25BQ
					More data for this Ligand-Target Pair