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SMILES: NC(=O)CC[C@H](NC(=O)[C@@H]1Cc2cccc3CC[C@H](NC(=O)c4cc5cc(OP(O)(O)=O)ccc5[nH]4)C(=O)N1c23)C(=O)NCc1ccccc1

InChI Key: InChIKey=AZRSLUWQORPJPG-NSVAZKTRSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50267453   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Signal transducer and activator of transcription 3


(Homo sapiens (Human))		BDBM50267453
PNG
(2-((3S,6S)-6-((S)-5-amino-1-(benzylamino)-1,5-diox...)
Show SMILES NC(=O)CC[C@H](NC(=O)[C@@H]1Cc2cccc3CC[C@H](NC(=O)c4cc5cc(OP(O)(O)=O)ccc5[nH]4)C(=O)N1c23)C(=O)NCc1ccccc1 |r|
Show InChI InChI=1S/C34H35N6O9P/c35-29(41)14-13-25(31(42)36-18-19-5-2-1-3-6-19)38-33(44)28-17-21-8-4-7-20-9-11-26(34(45)40(28)30(20)21)39-32(43)27-16-22-15-23(49-50(46,47)48)10-12-24(22)37-27/h1-8,10,12,15-16,25-26,28,37H,9,11,13-14,17-18H2,(H2,35,41)(H,36,42)(H,38,44)(H,39,43)(H2,46,47,48)/t25-,26-,28-/m0/s1
PDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 190n/an/an/an/an/an/a



The University of Texas M. D. Anderson Cancer Center

Curated by ChEMBL


Assay Description
Inhibition of Stat3 (unknown origin) by fluorescence polarization assay

J Med Chem 52: 2429-42 (2009)


Article DOI: 10.1021/jm801491w
BindingDB Entry DOI: 10.7270/Q28C9W4V
More data for this
Ligand-Target Pair