BDBM50267462 3-(5-Fluoro-1-methyl-1H-indol-3-yl)-4-(6-methoxymethylbenzofuran-3-yl)pyrrole-2,5-dione::CHEMBL516261

SMILES: COCc1ccc2c(coc2c1)C1=C(C(=O)NC1=O)c1cn(C)c2ccc(F)cc12

InChI Key: InChIKey=GQQMDLYMWXOHAK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50267462   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50267462 (3-(5-Fluoro-1-methyl-1H-indol-3-yl)-4-(6-methoxyme...) Show SMILES COCc1ccc2c(coc2c1)C1=C(C(=O)NC1=O)c1cn(C)c2ccc(F)cc12 |t:14| Show InChI InChI=1S/C23H17FN2O4/c1-26-9-16(15-8-13(24)4-6-18(15)26)20-21(23(28)25-22(20)27)17-11-30-19-7-12(10-29-2)3-5-14(17)19/h3-9,11H,10H2,1-2H3,(H,25,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human GSK3-beta by scintillation counting				J Med Chem 52: 1853-63 (2009) Article DOI: 10.1021/jm801317h BindingDB Entry DOI: 10.7270/Q24M94FZ
					More data for this Ligand-Target Pair