BDBM50267531 4-[Hydroxy(diphenyl)methyl]-1-propyl-1-azoniabicyclo[2.2.2]-octane Bromide::CHEMBL522632

SMILES: CCC[N+]12CCC(CC1)(CC2)C(O)(c1ccccc1)c1ccccc1

InChI Key: InChIKey=FKOCUINLFFLKCK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50267531   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50267531 (4-[Hydroxy(diphenyl)methyl]-1-propyl-1-azoniabicyc...) Show SMILES CCC[N+]12CCC(CC1)(CC2)C(O)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H30NO/c1-2-16-24-17-13-22(14-18-24,15-19-24)23(25,20-9-5-3-6-10-20)21-11-7-4-8-12-21/h3-12,25H,2,13-19H2,1H3/q+1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.08E+5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human cloned muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilizatio...				J Med Chem 52: 2493-505 (2009) Article DOI: 10.1021/jm801601v BindingDB Entry DOI: 10.7270/Q2H131X8
					More data for this Ligand-Target Pair