BDBM50267557 4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-pmethoxyphenylethyl)-piperidine::CHEMBL489408

SMILES: COc1ccc(CCN2CCC(CC2)C(=O)c2cccc(OCCF)c2OC)cc1

InChI Key: InChIKey=GWHHZSAHAOWCRM-UHFFFAOYSA-N

Data: 11 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50267557   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50267557 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-pmet...) Show SMILES COc1ccc(CCN2CCC(CC2)C(=O)c2cccc(OCCF)c2OC)cc1 Show InChI InChI=1S/C24H30FNO4/c1-28-20-8-6-18(7-9-20)10-14-26-15-11-19(12-16-26)23(27)21-4-3-5-22(24(21)29-2)30-17-13-25/h3-9,19H,10-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	153	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Displacement of [3H]MDL from rat 5HT2A receptor expressed in GF62 cells by liquid scintillation analyser				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50267557 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-pmet...) Show SMILES COc1ccc(CCN2CCC(CC2)C(=O)c2cccc(OCCF)c2OC)cc1 Show InChI InChI=1S/C24H30FNO4/c1-28-20-8-6-18(7-9-20)10-14-26-15-11-19(12-16-26)23(27)21-4-3-5-22(24(21)29-2)30-17-13-25/h3-9,19H,10-17H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	991	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned 5HT1A receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50267557 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-pmet...) Show SMILES COc1ccc(CCN2CCC(CC2)C(=O)c2cccc(OCCF)c2OC)cc1 Show InChI InChI=1S/C24H30FNO4/c1-28-20-8-6-18(7-9-20)10-14-26-15-11-19(12-16-26)23(27)21-4-3-5-22(24(21)29-2)30-17-13-25/h3-9,19H,10-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.44E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned 5HT1D receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50267557 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-pmet...) Show SMILES COc1ccc(CCN2CCC(CC2)C(=O)c2cccc(OCCF)c2OC)cc1 Show InChI InChI=1S/C24H30FNO4/c1-28-20-8-6-18(7-9-20)10-14-26-15-11-19(12-16-26)23(27)21-4-3-5-22(24(21)29-2)30-17-13-25/h3-9,19H,10-17H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.97E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned 5HT2B receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50267557 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-pmet...) Show SMILES COc1ccc(CCN2CCC(CC2)C(=O)c2cccc(OCCF)c2OC)cc1 Show InChI InChI=1S/C24H30FNO4/c1-28-20-8-6-18(7-9-20)10-14-26-15-11-19(12-16-26)23(27)21-4-3-5-22(24(21)29-2)30-17-13-25/h3-9,19H,10-17H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.86E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned 5HT7 receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50267557 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-pmet...) Show SMILES COc1ccc(CCN2CCC(CC2)C(=O)c2cccc(OCCF)c2OC)cc1 Show InChI InChI=1S/C24H30FNO4/c1-28-20-8-6-18(7-9-20)10-14-26-15-11-19(12-16-26)23(27)21-4-3-5-22(24(21)29-2)30-17-13-25/h3-9,19H,10-17H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.42E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned 5-HT2C receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50267557 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-pmet...) Show SMILES COc1ccc(CCN2CCC(CC2)C(=O)c2cccc(OCCF)c2OC)cc1 Show InChI InChI=1S/C24H30FNO4/c1-28-20-8-6-18(7-9-20)10-14-26-15-11-19(12-16-26)23(27)21-4-3-5-22(24(21)29-2)30-17-13-25/h3-9,19H,10-17H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned 5HT6 receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM50267557 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-pmet...) Show SMILES COc1ccc(CCN2CCC(CC2)C(=O)c2cccc(OCCF)c2OC)cc1 Show InChI InChI=1S/C24H30FNO4/c1-28-20-8-6-18(7-9-20)10-14-26-15-11-19(12-16-26)23(27)21-4-3-5-22(24(21)29-2)30-17-13-25/h3-9,19H,10-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned 5HT3 receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50267557 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-pmet...) Show SMILES COc1ccc(CCN2CCC(CC2)C(=O)c2cccc(OCCF)c2OC)cc1 Show InChI InChI=1S/C24H30FNO4/c1-28-20-8-6-18(7-9-20)10-14-26-15-11-19(12-16-26)23(27)21-4-3-5-22(24(21)29-2)30-17-13-25/h3-9,19H,10-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned 5HT1B receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 5A (Homo sapiens (Human))	BDBM50267557 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-pmet...) Show SMILES COc1ccc(CCN2CCC(CC2)C(=O)c2cccc(OCCF)c2OC)cc1 Show InChI InChI=1S/C24H30FNO4/c1-28-20-8-6-18(7-9-20)10-14-26-15-11-19(12-16-26)23(27)21-4-3-5-22(24(21)29-2)30-17-13-25/h3-9,19H,10-17H2,1-2H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned 5HT5A receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Homo sapiens (Human))	BDBM50267557 (4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-pmet...) Show SMILES COc1ccc(CCN2CCC(CC2)C(=O)c2cccc(OCCF)c2OC)cc1 Show InChI InChI=1S/C24H30FNO4/c1-28-20-8-6-18(7-9-20)10-14-26-15-11-19(12-16-26)23(27)21-4-3-5-22(24(21)29-2)30-17-13-25/h3-9,19H,10-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Nuclear Chemistry Johannes Gutenberg-University Mainz Curated by ChEMBL					Assay Description Inhibition of human cloned 5HT1E receptor by competitive binding experiment				Bioorg Med Chem 17: 2989-3002 (2009) Article DOI: 10.1016/j.bmc.2009.03.021 BindingDB Entry DOI: 10.7270/Q21V5DW2
					More data for this Ligand-Target Pair