BDBM50267594 CHEMBL4103361

SMILES: [H][C@@]12CC[C@]3(C)[C@]([H])(CC(=O)C4=CCC[C@@]34C)[C@@]1(C)CC[C@H](O)C2(C)C

InChI Key: InChIKey=MLDXUANBJWSMDT-JPKYEYPISA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267594   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50267594 (CHEMBL4103361) Show SMILES [H][C@@]12CC[C@]3(C)[C@]([H])(CC(=O)C4=CCC[C@@]34C)[C@@]1(C)CC[C@H](O)C2(C)C |r,t:11| Show InChI InChI=1S/C22H34O2/c1-19(2)16-8-12-22(5)17(20(16,3)11-9-18(19)24)13-15(23)14-7-6-10-21(14,22)4/h7,16-18,24H,6,8-13H2,1-5H3/t16-,17+,18-,20-,21+,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China. Curated by ChEMBL					Assay Description Inhibition of full-length human 11beta-HSD1 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 2 hr by scintillation prox...				Eur J Med Chem 135: 324-338 (2017) Article DOI: 10.1016/j.ejmech.2017.04.059 BindingDB Entry DOI: 10.7270/Q2CF9SK2
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 2 (Homo sapiens (Human))	BDBM50267594 (CHEMBL4103361) Show SMILES [H][C@@]12CC[C@]3(C)[C@]([H])(CC(=O)C4=CCC[C@@]34C)[C@@]1(C)CC[C@H](O)C2(C)C |r,t:11| Show InChI InChI=1S/C22H34O2/c1-19(2)16-8-12-22(5)17(20(16,3)11-9-18(19)24)13-15(23)14-7-6-10-21(14,22)4/h7,16-18,24H,6,8-13H2,1-5H3/t16-,17+,18-,20-,21+,22+/m0/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China. Curated by ChEMBL					Assay Description Inhibition of full-length human 11beta-HSD2 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 2 hr by scintillation prox...				Eur J Med Chem 135: 324-338 (2017) Article DOI: 10.1016/j.ejmech.2017.04.059 BindingDB Entry DOI: 10.7270/Q2CF9SK2
					More data for this Ligand-Target Pair