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SMILES: OC(c1ccccc1)(c1ccccc1)C12CC[N+](CCCCOc3ccccc3)(CC1)CC2

InChI Key: InChIKey=SRHIFBZHPRAPCK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50267611   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))		BDBM50267611
PNG
(4-[Hydroxy(diphenyl)methyl]-1-[4-(phenyloxy)butyl]...)
Show SMILES OC(c1ccccc1)(c1ccccc1)C12CC[N+](CCCCOc3ccccc3)(CC1)CC2
Show InChI InChI=1S/C30H36NO2/c32-30(26-12-4-1-5-13-26,27-14-6-2-7-15-27)29-18-22-31(23-19-29,24-20-29)21-10-11-25-33-28-16-8-3-9-17-28/h1-9,12-17,32H,10-11,18-25H2/q+1
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Article
PubMed
n/an/a 9.50E+3n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human cloned muscarinic M3 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilizatio...

J Med Chem 52: 2493-505 (2009)


Article DOI: 10.1021/jm801601v
BindingDB Entry DOI: 10.7270/Q2H131X8
More data for this
Ligand-Target Pair