BDBM50267869 CHEMBL522262::cyclohexyl(2-methyl-4-(naphthalen-1-ylsulfonyl)piperazin-1-yl)methanone

SMILES: CC1CN(CCN1C(=O)C1CCCCC1)S(=O)(=O)c1cccc2ccccc12

InChI Key: InChIKey=RRMJGXWUBNPGIF-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267869   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50267869 (CHEMBL522262 | cyclohexyl(2-methyl-4-(naphthalen-1...) Show SMILES CC1CN(CCN1C(=O)C1CCCCC1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C22H28N2O3S/c1-17-16-23(14-15-24(17)22(25)19-9-3-2-4-10-19)28(26,27)21-13-7-11-18-8-5-6-12-20(18)21/h5-8,11-13,17,19H,2-4,9-10,14-16H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inverse agonist activity at human recombinant CB1R expressed in CHO cells assessed as increase in forskolin-stimulated cAMP level				J Med Chem 52: 2550-8 (2009) Article DOI: 10.1021/jm900063x BindingDB Entry DOI: 10.7270/Q2028RF8
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50267869 (CHEMBL522262 | cyclohexyl(2-methyl-4-(naphthalen-1...) Show SMILES CC1CN(CCN1C(=O)C1CCCCC1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C22H28N2O3S/c1-17-16-23(14-15-24(17)22(25)19-9-3-2-4-10-19)28(26,27)21-13-7-11-18-8-5-6-12-20(18)21/h5-8,11-13,17,19H,2-4,9-10,14-16H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from human recombinant CB1R expressed in CHO cells				J Med Chem 52: 2550-8 (2009) Article DOI: 10.1021/jm900063x BindingDB Entry DOI: 10.7270/Q2028RF8
					More data for this Ligand-Target Pair