BDBM50267880 (R)-5-Oxo-5-(2-(thiazole-2-carbonyl)hydrazinyl)-4-(3,4,5-trimethoxybenzamido)pentanoic acid::CHEMBL490844

SMILES: COc1cc(cc(OC)c1OC)C(=O)N[C@H](CCC(O)=O)C(=O)NNC(=O)c1nccs1

InChI Key: InChIKey=SWPKEZXSKUURJJ-LLVKDONJSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267880   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50267880 ((R)-5-Oxo-5-(2-(thiazole-2-carbonyl)hydrazinyl)-4-...) Show SMILES COc1cc(cc(OC)c1OC)C(=O)N[C@H](CCC(O)=O)C(=O)NNC(=O)c1nccs1 |r| Show InChI InChI=1S/C19H22N4O8S/c1-29-12-8-10(9-13(30-2)15(12)31-3)16(26)21-11(4-5-14(24)25)17(27)22-23-18(28)19-20-6-7-32-19/h6-9,11H,4-5H2,1-3H3,(H,21,26)(H,22,27)(H,23,28)(H,24,25)/t11-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.69E+5	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of MMP2 by spectrophotometry				Bioorg Med Chem 17: 3053-60 (2009) Article DOI: 10.1016/j.bmc.2009.02.063 BindingDB Entry DOI: 10.7270/Q2NP25BQ
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50267880 ((R)-5-Oxo-5-(2-(thiazole-2-carbonyl)hydrazinyl)-4-...) Show SMILES COc1cc(cc(OC)c1OC)C(=O)N[C@H](CCC(O)=O)C(=O)NNC(=O)c1nccs1 |r| Show InChI InChI=1S/C19H22N4O8S/c1-29-12-8-10(9-13(30-2)15(12)31-3)16(26)21-11(4-5-14(24)25)17(27)22-23-18(28)19-20-6-7-32-19/h6-9,11H,4-5H2,1-3H3,(H,21,26)(H,22,27)(H,23,28)(H,24,25)/t11-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.77E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of pig kidney microsome aminopeptidase N by UV-visible spectrophotometer				Bioorg Med Chem 17: 3053-60 (2009) Article DOI: 10.1016/j.bmc.2009.02.063 BindingDB Entry DOI: 10.7270/Q2NP25BQ
					More data for this Ligand-Target Pair