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BDBM50267894 CHEMBL4102505

SMILES: CCOc1ccc2nc3cc(NC(=O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F)ccc3c(N)c2c1

InChI Key: InChIKey=VAHGZHFLTNXOIZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50267894   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
STE20/SPS1-related proline-alanine-rich protein kinase


(Rattus norvegicus)		BDBM50267894
PNG
(CHEMBL4102505)
Show SMILES CCOc1ccc2nc3cc(NC(=O)c4cc(cc(c4)C(F)(F)F)C(F)(F)F)ccc3c(N)c2c1
Show InChI InChI=1S/C24H17F6N3O2/c1-2-35-16-4-6-19-18(11-16)21(31)17-5-3-15(10-20(17)33-19)32-22(34)12-7-13(23(25,26)27)9-14(8-12)24(28,29)30/h3-11H,2H2,1H3,(H2,31,33)(H,32,34)
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyodaku, Tokyo 101-0062, Japan.

Curated by ChEMBL


Assay Description
Inhibition of TAMRA-labelled WNK4 binding to recombinant rat C-terminal GST-fused SPAK (452 to 553 residues) expressed in Escherichia coli BL21 measu...

Bioorg Med Chem 25: 3845-3852 (2017)


Article DOI: 10.1016/j.bmc.2017.05.034
BindingDB Entry DOI: 10.7270/Q22Z1811
More data for this
Ligand-Target Pair