BDBM50267991 (R)-2-(3-(3-(4-methoxybenzoyl)-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl)phenoxy)butanoic acid::CHEMBL490029

SMILES: CC[C@@H](Oc1cccc(c1)-n1c(C)c(C(=O)c2ccc(OC)cc2)c2ccc(OC(F)(F)F)cc12)C(O)=O

InChI Key: InChIKey=STWITCBWQHTJFJ-XMMPIXPASA-N

Data: 2 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50267991   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50267991 ((R)-2-(3-(3-(4-methoxybenzoyl)-2-methyl-6-(trifluo...) Show SMILES CC[C@@H](Oc1cccc(c1)-n1c(C)c(C(=O)c2ccc(OC)cc2)c2ccc(OC(F)(F)F)cc12)C(O)=O |r| Show InChI InChI=1S/C28H24F3NO6/c1-4-24(27(34)35)37-20-7-5-6-18(14-20)32-16(2)25(26(33)17-8-10-19(36-3)11-9-17)22-13-12-21(15-23(22)32)38-28(29,30)31/h5-15,24H,4H2,1-3H3,(H,34,35)/t24-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from human recombinant GST-fused PPARalpha expressed in Escherichia coli by scintillation proximity assay				J Med Chem 52: 3846-54 (2009) Article DOI: 10.1021/jm900097m BindingDB Entry DOI: 10.7270/Q2GF0TDR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50267991 ((R)-2-(3-(3-(4-methoxybenzoyl)-2-methyl-6-(trifluo...) Show SMILES CC[C@@H](Oc1cccc(c1)-n1c(C)c(C(=O)c2ccc(OC)cc2)c2ccc(OC(F)(F)F)cc12)C(O)=O |r| Show InChI InChI=1S/C28H24F3NO6/c1-4-24(27(34)35)37-20-7-5-6-18(14-20)32-16(2)25(26(33)17-8-10-19(36-3)11-9-17)22-13-12-21(15-23(22)32)38-28(29,30)31/h5-15,24H,4H2,1-3H3,(H,34,35)/t24-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human recombinant PPARgamma expressed in COS1 cells coexpressing GAL4 assessed as transcriptional activity after 48 hrs by lucife...				J Med Chem 52: 3846-54 (2009) Article DOI: 10.1021/jm900097m BindingDB Entry DOI: 10.7270/Q2GF0TDR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Canis familiaris)	BDBM50267991 ((R)-2-(3-(3-(4-methoxybenzoyl)-2-methyl-6-(trifluo...) Show SMILES CC[C@@H](Oc1cccc(c1)-n1c(C)c(C(=O)c2ccc(OC)cc2)c2ccc(OC(F)(F)F)cc12)C(O)=O |r| Show InChI InChI=1S/C28H24F3NO6/c1-4-24(27(34)35)37-20-7-5-6-18(14-20)32-16(2)25(26(33)17-8-10-19(36-3)11-9-17)22-13-12-21(15-23(22)32)38-28(29,30)31/h5-15,24H,4H2,1-3H3,(H,34,35)/t24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	370	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at dog PPARalpha				J Med Chem 52: 3846-54 (2009) Article DOI: 10.1021/jm900097m BindingDB Entry DOI: 10.7270/Q2GF0TDR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Mus musculus)	BDBM50267991 ((R)-2-(3-(3-(4-methoxybenzoyl)-2-methyl-6-(trifluo...) Show SMILES CC[C@@H](Oc1cccc(c1)-n1c(C)c(C(=O)c2ccc(OC)cc2)c2ccc(OC(F)(F)F)cc12)C(O)=O |r| Show InChI InChI=1S/C28H24F3NO6/c1-4-24(27(34)35)37-20-7-5-6-18(14-20)32-16(2)25(26(33)17-8-10-19(36-3)11-9-17)22-13-12-21(15-23(22)32)38-28(29,30)31/h5-15,24H,4H2,1-3H3,(H,34,35)/t24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at mouse PPARalpha				J Med Chem 52: 3846-54 (2009) Article DOI: 10.1021/jm900097m BindingDB Entry DOI: 10.7270/Q2GF0TDR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50267991 ((R)-2-(3-(3-(4-methoxybenzoyl)-2-methyl-6-(trifluo...) Show SMILES CC[C@@H](Oc1cccc(c1)-n1c(C)c(C(=O)c2ccc(OC)cc2)c2ccc(OC(F)(F)F)cc12)C(O)=O |r| Show InChI InChI=1S/C28H24F3NO6/c1-4-24(27(34)35)37-20-7-5-6-18(14-20)32-16(2)25(26(33)17-8-10-19(36-3)11-9-17)22-13-12-21(15-23(22)32)38-28(29,30)31/h5-15,24H,4H2,1-3H3,(H,34,35)/t24-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H2]nTZD3 from human recombinant GST-fused PPARgamma expressed in Escherichia coli by scintillation proximity assay				J Med Chem 52: 3846-54 (2009) Article DOI: 10.1021/jm900097m BindingDB Entry DOI: 10.7270/Q2GF0TDR
					More data for this Ligand-Target Pair