BDBM50268532 3-oxo-N-(5-phenylpyrimidin-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-carboxamide::CHEMBL522388

SMILES: O=C(Nc1ncc(cn1)-c1ccccc1)N1CCC2(CC1)OC(=O)c1ccccc21

InChI Key: InChIKey=UQZIBYPLWBTFTR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50268532   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NPY5R (Rat 6B)	BDBM50268532 (3-oxo-N-(5-phenylpyrimidin-2-yl)-3H-spiro[isobenzo...) Show SMILES O=C(Nc1ncc(cn1)-c1ccccc1)N1CCC2(CC1)OC(=O)c1ccccc21 Show InChI InChI=1S/C23H20N4O3/c28-20-18-8-4-5-9-19(18)23(30-20)10-12-27(13-11-23)22(29)26-21-24-14-17(15-25-21)16-6-2-1-3-7-16/h1-9,14-15H,10-13H2,(H,24,25,26,29)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.670	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from rat NPY Y5 receptor				Bioorg Med Chem Lett 19: 3511-6 (2009) Article DOI: 10.1016/j.bmcl.2009.05.013 BindingDB Entry DOI: 10.7270/Q21C1WS5
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50268532 (3-oxo-N-(5-phenylpyrimidin-2-yl)-3H-spiro[isobenzo...) Show SMILES O=C(Nc1ncc(cn1)-c1ccccc1)N1CCC2(CC1)OC(=O)c1ccccc21 Show InChI InChI=1S/C23H20N4O3/c28-20-18-8-4-5-9-19(18)23(30-20)10-12-27(13-11-23)22(29)26-21-24-14-17(15-25-21)16-6-2-1-3-7-16/h1-9,14-15H,10-13H2,(H,24,25,26,29)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant NPY Y5 receptor expressed in mouse LMtk- cells				Bioorg Med Chem Lett 19: 3511-6 (2009) Article DOI: 10.1016/j.bmcl.2009.05.013 BindingDB Entry DOI: 10.7270/Q21C1WS5
					More data for this Ligand-Target Pair