BDBM50268623 CHEMBL4063942

SMILES: COc1cnc(nc1)N1CCC(CC1)c1coc2c(ncnc12)N1CCc2cc(ccc12)S(C)(=O)=O

InChI Key: InChIKey=XJCARUXXXKBIJK-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50268623   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50268623 (CHEMBL4063942) Show SMILES COc1cnc(nc1)N1CCC(CC1)c1coc2c(ncnc12)N1CCc2cc(ccc12)S(C)(=O)=O Show InChI InChI=1S/C25H26N6O4S/c1-34-18-12-26-25(27-13-18)30-8-5-16(6-9-30)20-14-35-23-22(20)28-15-29-24(23)31-10-7-17-11-19(36(2,32)33)3-4-21(17)31/h3-4,11-16H,5-10H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	310	n/a	n/a	n/a	n/a
Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD., 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan. Electronic address: t-kosizw@kowa.co.jp. Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in CHOK1 cells co-expressing CRE-luciferase incubated for 4 hrs by luciferase reporter gene assay				Bioorg Med Chem Lett 27: 3249-3253 (2017) Article DOI: 10.1016/j.bmcl.2017.06.034 BindingDB Entry DOI: 10.7270/Q2TB19CJ
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