BDBM50268638 CHEMBL4080356

SMILES: CCCc1cnc(nc1)N1CCC(CC1)n1nnc2c(Nc3ccc(cc3F)S(C)(=O)=O)ncnc12

InChI Key: InChIKey=XYLPUTDPNTYJCZ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50268638   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50268638 (CHEMBL4080356) Show SMILES CCCc1cnc(nc1)N1CCC(CC1)n1nnc2c(Nc3ccc(cc3F)S(C)(=O)=O)ncnc12 Show InChI InChI=1S/C23H26FN9O2S/c1-3-4-15-12-25-23(26-13-15)32-9-7-16(8-10-32)33-22-20(30-31-33)21(27-14-28-22)29-19-6-5-17(11-18(19)24)36(2,34)35/h5-6,11-14,16H,3-4,7-10H2,1-2H3,(H,27,28,29)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	82	n/a	n/a	n/a	n/a
Tokyo New Drug Research Laboratories, Pharmaceutical Division, Kowa Co., LTD., 2-17-43, Noguchicho, Higashimurayama, Tokyo 189-0022, Japan. Electronic address: t-kosizw@kowa.co.jp. Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in HEK293 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 27: 3249-3253 (2017) Article DOI: 10.1016/j.bmcl.2017.06.034 BindingDB Entry DOI: 10.7270/Q2TB19CJ
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