BDBM50268905 (2S,3S,5RS)-5-(2-(5-aminopentylamino)-2-oxoethyl)-N-hydroxy-2-(3-phenylpyrrolidine-1-carbonyl)piperidine-3-carboxamide::CHEMBL495797

SMILES: NCCCCCNC(=O)CC1CN[C@@H]([C@H](C1)C(=O)NO)C(=O)N1CCC(C1)c1ccccc1

InChI Key: InChIKey=VXPAAABROXRBQT-XHXISMBCSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50268905   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50268905 ((2S,3S,5RS)-5-(2-(5-aminopentylamino)-2-oxoethyl)-...) Show SMILES NCCCCCNC(=O)CC1CN[C@@H]([C@H](C1)C(=O)NO)C(=O)N1CCC(C1)c1ccccc1 |r| Show InChI InChI=1S/C24H37N5O4/c25-10-5-2-6-11-26-21(30)14-17-13-20(23(31)28-33)22(27-15-17)24(32)29-12-9-19(16-29)18-7-3-1-4-8-18/h1,3-4,7-8,17,19-20,22,27,33H,2,5-6,9-16,25H2,(H,26,30)(H,28,31)/t17?,19?,20-,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation Curated by ChEMBL					Assay Description Inhibition of human MMP9				Bioorg Med Chem Lett 19: 3525-30 (2009) Article DOI: 10.1016/j.bmcl.2009.04.143 BindingDB Entry DOI: 10.7270/Q2ST7PRT
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50268905 ((2S,3S,5RS)-5-(2-(5-aminopentylamino)-2-oxoethyl)-...) Show SMILES NCCCCCNC(=O)CC1CN[C@@H]([C@H](C1)C(=O)NO)C(=O)N1CCC(C1)c1ccccc1 |r| Show InChI InChI=1S/C24H37N5O4/c25-10-5-2-6-11-26-21(30)14-17-13-20(23(31)28-33)22(27-15-17)24(32)29-12-9-19(16-29)18-7-3-1-4-8-18/h1,3-4,7-8,17,19-20,22,27,33H,2,5-6,9-16,25H2,(H,26,30)(H,28,31)/t17?,19?,20-,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation Curated by ChEMBL					Assay Description Inhibition of human MMP3				Bioorg Med Chem Lett 19: 3525-30 (2009) Article DOI: 10.1016/j.bmcl.2009.04.143 BindingDB Entry DOI: 10.7270/Q2ST7PRT
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50268905 ((2S,3S,5RS)-5-(2-(5-aminopentylamino)-2-oxoethyl)-...) Show SMILES NCCCCCNC(=O)CC1CN[C@@H]([C@H](C1)C(=O)NO)C(=O)N1CCC(C1)c1ccccc1 |r| Show InChI InChI=1S/C24H37N5O4/c25-10-5-2-6-11-26-21(30)14-17-13-20(23(31)28-33)22(27-15-17)24(32)29-12-9-19(16-29)18-7-3-1-4-8-18/h1,3-4,7-8,17,19-20,22,27,33H,2,5-6,9-16,25H2,(H,26,30)(H,28,31)/t17?,19?,20-,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation Curated by ChEMBL					Assay Description Inhibition of human MMP2				Bioorg Med Chem Lett 19: 3525-30 (2009) Article DOI: 10.1016/j.bmcl.2009.04.143 BindingDB Entry DOI: 10.7270/Q2ST7PRT
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10) (Homo sapiens (Human))	BDBM50268905 ((2S,3S,5RS)-5-(2-(5-aminopentylamino)-2-oxoethyl)-...) Show SMILES NCCCCCNC(=O)CC1CN[C@@H]([C@H](C1)C(=O)NO)C(=O)N1CCC(C1)c1ccccc1 |r| Show InChI InChI=1S/C24H37N5O4/c25-10-5-2-6-11-26-21(30)14-17-13-20(23(31)28-33)22(27-15-17)24(32)29-12-9-19(16-29)18-7-3-1-4-8-18/h1,3-4,7-8,17,19-20,22,27,33H,2,5-6,9-16,25H2,(H,26,30)(H,28,31)/t17?,19?,20-,22-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	161	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation Curated by ChEMBL					Assay Description Inhibition of human recombinant ADAM10				Bioorg Med Chem Lett 19: 3525-30 (2009) Article DOI: 10.1016/j.bmcl.2009.04.143 BindingDB Entry DOI: 10.7270/Q2ST7PRT
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50268905 ((2S,3S,5RS)-5-(2-(5-aminopentylamino)-2-oxoethyl)-...) Show SMILES NCCCCCNC(=O)CC1CN[C@@H]([C@H](C1)C(=O)NO)C(=O)N1CCC(C1)c1ccccc1 |r| Show InChI InChI=1S/C24H37N5O4/c25-10-5-2-6-11-26-21(30)14-17-13-20(23(31)28-33)22(27-15-17)24(32)29-12-9-19(16-29)18-7-3-1-4-8-18/h1,3-4,7-8,17,19-20,22,27,33H,2,5-6,9-16,25H2,(H,26,30)(H,28,31)/t17?,19?,20-,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation Curated by ChEMBL					Assay Description Inhibition of human MMP1				Bioorg Med Chem Lett 19: 3525-30 (2009) Article DOI: 10.1016/j.bmcl.2009.04.143 BindingDB Entry DOI: 10.7270/Q2ST7PRT
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50268905 ((2S,3S,5RS)-5-(2-(5-aminopentylamino)-2-oxoethyl)-...) Show SMILES NCCCCCNC(=O)CC1CN[C@@H]([C@H](C1)C(=O)NO)C(=O)N1CCC(C1)c1ccccc1 |r| Show InChI InChI=1S/C24H37N5O4/c25-10-5-2-6-11-26-21(30)14-17-13-20(23(31)28-33)22(27-15-17)24(32)29-12-9-19(16-29)18-7-3-1-4-8-18/h1,3-4,7-8,17,19-20,22,27,33H,2,5-6,9-16,25H2,(H,26,30)(H,28,31)/t17?,19?,20-,22-/m0/s1	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	162	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation Curated by ChEMBL					Assay Description Inhibition of HER2 extracellular domain sheddase activity in human BT474 cells after 72 hrs by ELISA				Bioorg Med Chem Lett 19: 3525-30 (2009) Article DOI: 10.1016/j.bmcl.2009.04.143 BindingDB Entry DOI: 10.7270/Q2ST7PRT
					More data for this Ligand-Target Pair