BDBM50268943 CHEMBL4089778

SMILES: CCc1cnc(nc1)N1CCC(COc2ccc(nc2)-c2ccc(C(=O)N(C)OC)c(F)c2)CC1

InChI Key: InChIKey=FMBAIPKCWKWRAK-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50268943   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucose-dependent insulinotropic receptor (Homo sapiens (Human))	BDBM50268943 (CHEMBL4089778) Show SMILES CCc1cnc(nc1)N1CCC(COc2ccc(nc2)-c2ccc(C(=O)N(C)OC)c(F)c2)CC1 Show InChI InChI=1S/C26H30FN5O3/c1-4-18-14-29-26(30-15-18)32-11-9-19(10-12-32)17-35-21-6-8-24(28-16-21)20-5-7-22(23(27)13-20)25(33)31(2)34-3/h5-8,13-16,19H,4,9-12,17H2,1-3H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	77	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in CHOK1 cells harboring CRE-luciferase after 6 hrs by luciferase reporter gene assay				Bioorg Med Chem Lett 27: 3909-3914 (2017) Article DOI: 10.1016/j.bmcl.2017.06.032 BindingDB Entry DOI: 10.7270/Q2NK3HHF
					More data for this Ligand-Target Pair