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BDBM50269664 CHEMBL4076657

SMILES: COc1cc(ccc1O)C(OC1CCCCC1)C(C)Oc1c(OC)cc(CC=C)cc1OC

InChI Key: InChIKey=IOMWMZXLSBIPLQ-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50269664   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily M member 8 (TRPM8)


(Homo sapiens (Human))		BDBM50269664
PNG
(CHEMBL4076657)
Show SMILES COc1cc(ccc1O)C(OC1CCCCC1)C(C)Oc1c(OC)cc(CC=C)cc1OC
Show InChI InChI=1S/C27H36O6/c1-6-10-19-15-24(30-4)27(25(16-19)31-5)32-18(2)26(33-21-11-8-7-9-12-21)20-13-14-22(28)23(17-20)29-3/h6,13-18,21,26,28H,1,7-12H2,2-5H3
KEGG

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PC cid
PC sid
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Similars
Article
PubMed
n/an/an/an/a 54n/an/an/an/a



Kansei Science Research and Biological Science Research, Kao Corporation, 2606 Akabane, Ichikai-Machi, Haga-Gun, Tochigi 321-3497, Japan.

Curated by ChEMBL


Assay Description
Agonist activity at full length recombinant human TRPM8 expressed in HEK293 cells assessed as increase in intracellular Ca2+ level pre-incubated for ...

ACS Med Chem Lett 8: 715-719 (2017)


Article DOI: 10.1021/acsmedchemlett.7b00104
BindingDB Entry DOI: 10.7270/Q2CZ39N2
More data for this
Ligand-Target Pair