BDBM50269940 (2S,5S)-2-Hydroxymethyl-5-[1'-(2'-phenyl)-ethynyl]-1-aza-bicyclo-[2.2.2]-octane::CHEMBL391926
SMILES: OC[C@@H]1CC2CCN1C[C@@H]2C#Cc1ccccc1
InChI Key: InChIKey=OFNRRJIDWMSULE-YVZMLIKISA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Farnesyltransferase, putative (Leishmania major) | BDBM50269940 ((2S,5S)-2-Hydroxymethyl-5-[1'-(2'-phenyl)-ethynyl]...) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Cardiff University Curated by ChEMBL | Assay Description Inhibition of Leishmania major recombinant squalene synthase expressed in Escherichia coli by liquid scintillation counter | Antimicrob Agents Chemother 51: 4049-61 (2007) Article DOI: 10.1128/AAC.00205-07 BindingDB Entry DOI: 10.7270/Q2MS3SJZ | |||||||||||
More data for this Ligand-Target Pair |