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SMILES: CC(=O)Nc1ccc(cc1)S(=O)(=O)n1cc(c2c1C=CC(=O)C2=O)-c1ccccc1

InChI Key: InChIKey=RPCMHQGXYJFAMG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50269996   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ELAV-like protein 1


(Homo sapiens (Human))		BDBM50269996
PNG
(CHEMBL4094161)
Show SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)n1cc(c2c1C=CC(=O)C2=O)-c1ccccc1 |c:20|
Show InChI InChI=1S/C22H16N2O5S/c1-14(25)23-16-7-9-17(10-8-16)30(28,29)24-13-18(15-5-3-2-4-6-15)21-19(24)11-12-20(26)22(21)27/h2-13H,1H3,(H,23,25)
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Article
PubMed
 81n/an/an/an/an/an/an/an/a



Institute of Molecular Science and Technology (ISTM)

Curated by ChEMBL


Assay Description
Binding affinity to human full length recombinant His-tagged HuR expressed in Escherichia coli Rosetta DH5alpha assessed as inhibition of interaction...

J Med Chem 61: 1483-1498 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01176
BindingDB Entry DOI: 10.7270/Q2Q81GKP
More data for this
Ligand-Target Pair