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BDBM50270285 (E/Z)-3-[4'-Carbonylbenzylidene]-quinuclidine::CHEMBL478359

SMILES: O=Cc1ccc(\C=C2/CN3CCC2CC3)cc1

InChI Key: InChIKey=WHMBRGWAMLKWOZ-OQLLNIDSSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50270285   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Farnesyltransferase, putative


(Leishmania major)		BDBM50270285
PNG
((E/Z)-3-[4'-Carbonylbenzylidene]-quinuclidine | CH...)
Show SMILES O=Cc1ccc(\C=C2/CN3CCC2CC3)cc1 |(-1.72,-10.71,;-1.72,-9.17,;-3.05,-8.4,;-3.06,-6.85,;-4.39,-6.09,;-5.71,-6.86,;-7.04,-6.08,;-8.38,-6.85,;-8.38,-8.4,;-9.72,-9.17,;-11.05,-8.4,;-11.05,-6.85,;-9.72,-6.07,;-10.46,-7.43,;-8.97,-7.84,;-5.72,-8.4,;-4.39,-9.16,)|
Show InChI InChI=1S/C15H17NO/c17-11-13-3-1-12(2-4-13)9-15-10-16-7-5-14(15)6-8-16/h1-4,9,11,14H,5-8,10H2/b15-9+
KEGG

UniProtKB/TrEMBL

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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Cardiff University

Curated by ChEMBL


Assay Description
Inhibition of Leishmania major recombinant squalene synthase expressed in Escherichia coli by liquid scintillation counter

Antimicrob Agents Chemother 51: 4049-61 (2007)


Article DOI: 10.1128/AAC.00205-07
BindingDB Entry DOI: 10.7270/Q2MS3SJZ
More data for this
Ligand-Target Pair