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BDBM50270301 3-benzylquinuclidine::CHEMBL478913

SMILES: C(C1CN2CCC1CC2)c1ccccc1

InChI Key: InChIKey=YWLRVKNQQQOFJH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50270301   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Farnesyltransferase, putative


(Leishmania major)		BDBM50270301
PNG
(3-benzylquinuclidine | CHEMBL478913)
Show SMILES C(C1CN2CCC1CC2)c1ccccc1 |(10.4,-17.69,;9.07,-18.46,;9.07,-20.01,;7.72,-20.78,;6.39,-20.01,;6.39,-18.46,;7.72,-17.68,;6.99,-19.04,;8.48,-19.45,;11.73,-18.46,;13.05,-17.69,;14.39,-18.46,;14.39,-20.01,;13.06,-20.77,;11.72,-20,)|
Show InChI InChI=1S/C14H19N/c1-2-4-12(5-3-1)10-14-11-15-8-6-13(14)7-9-15/h1-5,13-14H,6-11H2
KEGG

UniProtKB/TrEMBL

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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Cardiff University

Curated by ChEMBL


Assay Description
Inhibition of Leishmania major recombinant squalene synthase expressed in Escherichia coli by liquid scintillation counter

Antimicrob Agents Chemother 51: 4049-61 (2007)


Article DOI: 10.1128/AAC.00205-07
BindingDB Entry DOI: 10.7270/Q2MS3SJZ
More data for this
Ligand-Target Pair