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BDBM50270680 CHEMBL482677::[5-(4-Chlorophenyl)furan-2-yl]-(4-methylpiperazin-1-yl)-methanone

SMILES: CN1CCN(CC1)C(=O)c1ccc(o1)-c1ccc(Cl)cc1

InChI Key: InChIKey=FTDIEBSIUGZEPF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50270680   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium channel protein type X alpha subunit


(Mus musculus)
BDBM50270680
PNG
(CHEMBL482677 | [5-(4-Chlorophenyl)furan-2-yl]-(4-m...)
Show SMILES CN1CCN(CC1)C(=O)c1ccc(o1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C16H17ClN2O2/c1-18-8-10-19(11-9-18)16(20)15-7-6-14(21-15)12-2-4-13(17)5-3-12/h2-7H,8-11H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.90E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of mouse recombinant Nav1.8 channel expressed in HEK293 cells by isotopic efflux assay


Bioorg Med Chem 16: 6379-86 (2008)


Article DOI: 10.1016/j.bmc.2008.05.003
BindingDB Entry DOI: 10.7270/Q2VH5NNT
More data for this
Ligand-Target Pair