null

SMILES: CC(=O)c1c(OCCCCN2CCN(CC2)c2cccc(Cl)c2Cl)ccc2c(C)cc(=O)oc12

InChI Key: InChIKey=LQJVAQOUDQLGKX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50270697   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50270697 (CHEMBL4126092) Show SMILES CC(=O)c1c(OCCCCN2CCN(CC2)c2cccc(Cl)c2Cl)ccc2c(C)cc(=O)oc12 Show InChI InChI=1S/C26H28Cl2N2O4/c1-17-16-23(32)34-26-19(17)8-9-22(24(26)18(2)31)33-15-4-3-10-29-11-13-30(14-12-29)21-7-5-6-20(27)25(21)28/h5-9,16H,3-4,10-15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Warsaw Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting method				Eur J Med Chem 137: 108-116 (2017) Article DOI: 10.1016/j.ejmech.2017.05.047 BindingDB Entry DOI: 10.7270/Q24B33TF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50270697 (CHEMBL4126092) Show SMILES CC(=O)c1c(OCCCCN2CCN(CC2)c2cccc(Cl)c2Cl)ccc2c(C)cc(=O)oc12 Show InChI InChI=1S/C26H28Cl2N2O4/c1-17-16-23(32)34-26-19(17)8-9-22(24(26)18(2)31)33-15-4-3-10-29-11-13-30(14-12-29)21-7-5-6-20(27)25(21)28/h5-9,16H,3-4,10-15H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Warsaw Curated by ChEMBL					Assay Description Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting method				Eur J Med Chem 137: 108-116 (2017) Article DOI: 10.1016/j.ejmech.2017.05.047 BindingDB Entry DOI: 10.7270/Q24B33TF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50270697 (CHEMBL4126092) Show SMILES CC(=O)c1c(OCCCCN2CCN(CC2)c2cccc(Cl)c2Cl)ccc2c(C)cc(=O)oc12 Show InChI InChI=1S/C26H28Cl2N2O4/c1-17-16-23(32)34-26-19(17)8-9-22(24(26)18(2)31)33-15-4-3-10-29-11-13-30(14-12-29)21-7-5-6-20(27)25(21)28/h5-9,16H,3-4,10-15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Warsaw Curated by ChEMBL					Assay Description Antagonist activity at human 5-HT1A receptor expressed in CHO-K1 cells assessed as inhibition of serotonin-induced calcium mobilization preincubated ...				Eur J Med Chem 137: 108-116 (2017) Article DOI: 10.1016/j.ejmech.2017.05.047 BindingDB Entry DOI: 10.7270/Q24B33TF
					More data for this Ligand-Target Pair