BDBM50271283 1-{3-[(6-Chloronaphthalen-2-yl)sulfonyl]propanoyl}-4-(2-methyl-1H-imidazol-1-yl)piperidine::CHEMBL482889

SMILES: Cc1nccn1C1CCN(CC1)C(=O)CCS(=O)(=O)c1ccc2cc(Cl)ccc2c1

InChI Key: InChIKey=NIMYXAUZJNYXPR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50271283   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50271283 (1-{3-[(6-Chloronaphthalen-2-yl)sulfonyl]propanoyl}...) Show SMILES Cc1nccn1C1CCN(CC1)C(=O)CCS(=O)(=O)c1ccc2cc(Cl)ccc2c1 Show InChI InChI=1S/C22H24ClN3O3S/c1-16-24-9-12-26(16)20-6-10-25(11-7-20)22(27)8-13-30(28,29)21-5-3-17-14-19(23)4-2-18(17)15-21/h2-5,9,12,14-15,20H,6-8,10-11,13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human factor 10a				J Med Chem 51: 3422-36 (2008) Article DOI: 10.1021/jm701548u BindingDB Entry DOI: 10.7270/Q2Z89C6Q
					More data for this Ligand-Target Pair