BDBM50271979 1-(3-fluoro-4-(3-(hydroxymethyl)-1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl)-3-(2-(4-fluorophenyl)acetyl)urea::CHEMBL499886

SMILES: OCc1c[nH]c2nccc(Oc3ccc(NC(=O)NC(=O)Cc4ccc(F)cc4)cc3F)c12

InChI Key: InChIKey=DYFJYOVDYFGZDE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50271979   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50271979 (1-(3-fluoro-4-(3-(hydroxymethyl)-1H-pyrrolo[2,3-b]...) Show SMILES OCc1c[nH]c2nccc(Oc3ccc(NC(=O)NC(=O)Cc4ccc(F)cc4)cc3F)c12 Show InChI InChI=1S/C23H18F2N4O4/c24-15-3-1-13(2-4-15)9-20(31)29-23(32)28-16-5-6-18(17(25)10-16)33-19-7-8-26-22-21(19)14(12-30)11-27-22/h1-8,10-11,30H,9,12H2,(H,26,27)(H2,28,29,31,32)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of human c-MET				Eur J Med Chem 46: 3675-80 (2011) Article DOI: 10.1016/j.ejmech.2011.05.031 BindingDB Entry DOI: 10.7270/Q2891676
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50271979 (1-(3-fluoro-4-(3-(hydroxymethyl)-1H-pyrrolo[2,3-b]...) Show SMILES OCc1c[nH]c2nccc(Oc3ccc(NC(=O)NC(=O)Cc4ccc(F)cc4)cc3F)c12 Show InChI InChI=1S/C23H18F2N4O4/c24-15-3-1-13(2-4-15)9-20(31)29-23(32)28-16-5-6-18(17(25)10-16)33-19-7-8-26-22-21(19)14(12-30)11-27-22/h1-8,10-11,30H,9,12H2,(H,26,27)(H2,28,29,31,32)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of Met kinase (unknown origin)				Bioorg Med Chem Lett 18: 3224-9 (2008) Article DOI: 10.1016/j.bmcl.2008.04.047 BindingDB Entry DOI: 10.7270/Q2XG9QX1
					More data for this Ligand-Target Pair