BDBM50271998 CHEMBL4127302
SMILES: COc1ccc(cc1OC)C(C)(C)c1cnc(SCCOCc2ccc(cc2)C#N)n1-c1ccc(F)cc1
InChI Key: InChIKey=LLBRZFXGFGQSFK-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
G-protein coupled bile acid receptor 1 (Homo sapiens (Human)) | BDBM50271998 (CHEMBL4127302) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a |
Cadila Healthcare Ltd. Curated by ChEMBL | Assay Description Inhibition of human DNA polymerase delta assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins | Bioorg Med Chem Lett 28: 1849-1852 (2018) Article DOI: 10.1016/j.bmcl.2018.04.011 BindingDB Entry DOI: 10.7270/Q2BP0588 | |||||||||||
More data for this Ligand-Target Pair |