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SMILES: FC(F)(F)c1cccc(c1)N1CCC(CC1)C(=O)Nc1cnc2ccccc2c1

InChI Key: InChIKey=UUBMKYMKHNKKME-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50272784   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50272784
PNG
(CHEMBL498653 | N-(quinolin-3-yl)-1-(3-(trifluorome...)
Show SMILES FC(F)(F)c1cccc(c1)N1CCC(CC1)C(=O)Nc1cnc2ccccc2c1
Show InChI InChI=1S/C22H20F3N3O/c23-22(24,25)17-5-3-6-19(13-17)28-10-8-15(9-11-28)21(29)27-18-12-16-4-1-2-7-20(16)26-14-18/h1-7,12-15H,8-11H2,(H,27,29)
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Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux by FLIPR

Bioorg Med Chem Lett 18: 4569-72 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.035
BindingDB Entry DOI: 10.7270/Q2154GV5
More data for this
Ligand-Target Pair