BDBM50273168 2-(methoxymethyl)-7-(3-(trifluoromethyl)pyridin-2-yl)-N-(5-(trifluoromethyl)pyridin-2-yl)quinazolin-4-amine::CHEMBL456572

SMILES: COCc1nc(Nc2ccc(cn2)C(F)(F)F)c2ccc(cc2n1)-c1ncccc1C(F)(F)F

InChI Key: InChIKey=DGOMZWWTBMNQBA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50273168   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50273168 (2-(methoxymethyl)-7-(3-(trifluoromethyl)pyridin-2-...) Show SMILES COCc1nc(Nc2ccc(cn2)C(F)(F)F)c2ccc(cc2n1)-c1ncccc1C(F)(F)F Show InChI InChI=1S/C22H15F6N5O/c1-34-11-18-31-16-9-12(19-15(22(26,27)28)3-2-8-29-19)4-6-14(16)20(33-18)32-17-7-5-13(10-30-17)21(23,24)25/h2-10H,11H2,1H3,(H,30,31,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Neurogen Corporation Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 receptor assessed as inhibition of capsaicin-induced activation				Bioorg Med Chem Lett 18: 4573-7 (2008) Article DOI: 10.1016/j.bmcl.2008.07.036 BindingDB Entry DOI: 10.7270/Q28P6099
					More data for this Ligand-Target Pair