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BDBM50273606 CHEMBL4126506

SMILES: OC1(CC(=NN1C(=O)Cc1ccccc1)c1cccc(Cl)c1)C(F)(F)F

InChI Key: InChIKey=SFDXZMFPSQQEHV-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50273606   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Calcium release-activated calcium channel


(Homo sapiens (Human))		BDBM50273606
PNG
(CHEMBL4126506)
Show SMILES OC1(CC(=NN1C(=O)Cc1ccccc1)c1cccc(Cl)c1)C(F)(F)F |c:3|
Show InChI InChI=1S/C18H14ClF3N2O2/c19-14-8-4-7-13(10-14)15-11-17(26,18(20,21)22)24(23-15)16(25)9-12-5-2-1-3-6-12/h1-8,10,26H,9,11H2
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 4.80E+4n/an/an/an/an/an/a



University of Auckland

Curated by ChEMBL


Assay Description
Inhibition of BAPTA-induced Orai1-medited store operated calcium entry in human MDA-MB-231 cells pretreated for 15 mins followed by BAPTA addition by...

Bioorg Med Chem 26: 3406-3413 (2018)


Article DOI: 10.1016/j.bmc.2018.05.012
BindingDB Entry DOI: 10.7270/Q27S7R82
More data for this
Ligand-Target Pair