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BDBM50273765 (4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,40S)-4-(2-((2S,5S,8S,11S,20S)-11-((6S,12S,15S,18S,21S,24S,27S,30S,31S)-21-((1H-indol-3-yl)methyl)-1-amino-12-(4-aminobutyl)-27-benzyl-6-carbamoyl-1-imino-18-isobutyl-15-isopropyl-24,31-dimethyl-8,11,14,17,20,23,26,29-octaoxo-2,7,10,13,16,19,22,25,28-nonaazatritriacontan-30-ylcarbamoyl)-8-(4-aminobutyl)-2,5-dimethyl-3,6,9,14,21-pentaoxo-1,4,7,10,15-pentaazacyclohenicosan-20-ylamino)-2-oxoethylcarbamoyl)-40-((S)-2-((S)-2-amino-3-(1H-imidazol-5-yl)propanam::CHEMBL525235

SMILES: CC[C@H](C)[C@H](NC(=O)[C@@H]1CCC(=O)NCCCC[C@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O

InChI Key: InChIKey=YXZAHBKFVFYJIH-ZCYUXVDHSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50273765   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))		BDBM50273765
PNG
((4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,40S)-4-...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCC(=O)NCCCC[C@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O |r,wU:122.124,108.115,100.102,130.134,85.86,133.137,71.76,61.64,43.52,26.31,18.18,147.150,8.7,2.2,164.167,180.184,202.208,wD:117.119,89.98,79.82,67.68,55.58,35.39,142.145,152.155,4.4,175.180,194.200,209.215,222.228,(75.29,-8.17,;75.29,-6.62,;76.63,-5.85,;77.96,-6.62,;76.63,-4.32,;75.29,-3.55,;73.95,-4.32,;73.95,-5.86,;72.63,-3.55,;72.63,-2.01,;73.95,-1.24,;73.95,.31,;75.29,1.07,;72.62,1.08,;59.28,1.06,;57.95,.28,;57.95,-1.26,;56.62,-2.03,;56.62,-3.57,;55.28,-4.34,;53.95,-3.58,;53.95,-2.03,;52.61,-4.35,;51.28,-3.58,;49.95,-4.35,;49.95,-5.89,;48.61,-3.58,;48.61,-2.04,;49.95,-1.27,;49.95,.27,;48.61,1.04,;51.28,1.04,;47.27,-4.36,;45.95,-3.58,;45.95,-2.04,;44.61,-4.35,;44.61,-5.89,;45.95,-6.66,;45.95,-8.2,;47.28,-5.89,;43.27,-3.59,;41.94,-4.36,;41.94,-5.9,;40.61,-3.59,;40.61,-2.05,;41.94,-1.28,;43.27,-2.05,;44.6,-1.27,;44.6,.27,;45.93,1.04,;43.26,1.03,;41.94,.26,;39.27,-4.36,;37.94,-3.59,;37.94,-2.05,;36.61,-4.37,;36.61,-5.91,;37.94,-6.68,;35.27,-3.6,;33.94,-4.37,;33.94,-5.9,;32.61,-3.6,;32.61,-2.06,;33.94,-1.29,;31.27,-4.37,;29.94,-3.61,;29.94,-2.06,;28.6,-4.38,;27.27,-3.61,;25.94,-4.38,;25.94,-5.92,;24.6,-3.61,;24.6,-2.07,;25.94,-1.3,;27.26,-2.07,;25.94,.24,;23.26,-4.39,;21.94,-3.61,;21.94,-2.07,;20.6,-4.38,;20.6,-5.92,;21.94,-6.69,;19.26,-3.62,;17.93,-4.39,;17.93,-5.93,;16.6,-3.62,;15.26,-4.39,;13.93,-3.62,;13.93,-2.08,;12.59,-4.4,;12.59,-5.94,;13.93,-6.71,;15.27,-5.93,;16.59,-6.7,;16.6,-8.23,;15.26,-9.01,;13.93,-8.24,;11.26,-3.63,;9.93,-4.4,;9.93,-5.93,;8.59,-3.63,;7.26,-4.4,;5.93,-3.64,;5.93,-2.09,;4.59,-4.41,;3.26,-3.64,;1.92,-4.41,;1.92,-5.95,;.59,-3.64,;.59,-2.1,;1.92,-1.33,;1.92,.21,;.58,.98,;3.26,.98,;-.74,-4.42,;-2.07,-3.64,;-2.07,-2.1,;-3.41,-4.41,;-3.41,-5.95,;-4.75,-3.65,;-6.08,-4.41,;-6.08,-5.96,;-7.42,-3.65,;-8.75,-4.41,;-7.42,-2.11,;-6.08,-1.34,;-4.68,-1.96,;-3.65,-.81,;-4.42,.51,;-5.92,.19,;8.59,-2.09,;7.26,-1.31,;9.93,-1.32,;16.6,-2.08,;15.26,-1.31,;17.93,-1.31,;28.6,-5.91,;29.94,-6.68,;27.27,-6.68,;57.95,-4.34,;57.95,-5.87,;59.29,-3.57,;60.62,-4.34,;60.62,-5.88,;61.95,-3.56,;61.95,-2.02,;63.28,-4.33,;64.62,-3.56,;64.62,-2.02,;65.95,-4.33,;65.95,-5.87,;67.29,-3.56,;68.62,-4.32,;68.62,-5.86,;69.95,-6.63,;69.95,-8.17,;71.29,-8.95,;71.29,-10.48,;69.95,-3.55,;69.95,-2.01,;71.29,-4.33,;77.96,-3.55,;77.96,-2,;79.29,-4.31,;80.63,-3.54,;80.63,-1.99,;81.96,-1.23,;83.29,-1.99,;84.62,-1.23,;84.62,.31,;83.28,1.08,;81.96,.31,;81.96,-4.31,;81.96,-5.84,;83.3,-3.54,;84.63,-4.31,;84.63,-5.84,;85.96,-3.53,;85.96,-1.99,;87.3,-4.3,;88.63,-3.53,;88.63,-1.99,;89.96,-1.22,;91.37,-1.84,;92.39,-.69,;91.62,.63,;92.1,2.1,;91.07,3.24,;89.56,2.91,;89.09,1.45,;90.12,.31,;89.96,-4.3,;89.96,-5.84,;91.3,-3.53,;92.63,-4.3,;92.63,-5.83,;93.97,-6.6,;93.97,-8.14,;95.31,-5.83,;93.97,-3.52,;93.97,-1.98,;95.3,-4.3,;96.63,-3.53,;96.63,-1.98,;97.97,-1.21,;95.3,-1.21,;97.97,-4.29,;97.97,-5.83,;99.3,-3.52,;100.63,-4.29,;100.63,-5.82,;101.97,-6.59,;101.97,-8.13,;103.31,-8.9,;103.31,-10.44,;101.97,-3.52,;101.97,-1.98,;103.3,-4.28,;104.63,-3.51,;105.97,-4.28,;105.97,-5.82,;107.31,-3.51,;108.63,-4.28,;108.63,-5.82,;109.98,-6.59,;109.98,-8.12,;111.31,-8.89,;111.31,-10.43,;109.98,-11.2,;112.65,-11.2,;109.98,-3.51,;111.31,-4.27,;109.98,-1.96,)|
Show InChI InChI=1S/C150H228N40O43/c1-17-78(10)120(147(231)181-103(59-85-33-20-18-21-34-85)135(219)168-82(14)127(211)176-106(62-88-65-160-93-38-25-24-37-91(88)93)138(222)178-102(58-75(4)5)139(223)187-118(76(6)7)145(229)175-95(39-26-29-53-151)129(213)161-67-112(198)169-94(123(154)207)42-32-56-159-150(155)156)189-134(218)100-47-50-111(197)158-55-31-28-41-96(132(216)167-79(11)124(208)165-80(12)125(209)171-97(133(217)174-100)40-27-30-54-152)170-113(199)68-162-131(215)99(49-52-116(203)204)173-136(220)101(57-74(2)3)177-137(221)104(61-87-43-45-90(196)46-44-87)179-142(226)108(70-191)183-144(228)110(72-193)184-146(230)119(77(8)9)188-141(225)107(64-117(205)206)180-143(227)109(71-192)185-149(233)122(84(16)195)190-140(224)105(60-86-35-22-19-23-36-86)182-148(232)121(83(15)194)186-114(200)69-163-130(214)98(48-51-115(201)202)172-126(210)81(13)166-128(212)92(153)63-89-66-157-73-164-89/h18-25,33-38,43-46,65-66,73-84,92,94-110,118-122,160,191-196H,17,26-32,39-42,47-64,67-72,151-153H2,1-16H3,(H2,154,207)(H,157,164)(H,158,197)(H,161,213)(H,162,215)(H,163,214)(H,165,208)(H,166,212)(H,167,216)(H,168,219)(H,169,198)(H,170,199)(H,171,209)(H,172,210)(H,173,220)(H,174,217)(H,175,229)(H,176,211)(H,177,221)(H,178,222)(H,179,226)(H,180,227)(H,181,231)(H,182,232)(H,183,228)(H,184,230)(H,185,233)(H,186,200)(H,187,223)(H,188,225)(H,189,218)(H,190,224)(H,201,202)(H,203,204)(H,205,206)(H4,155,156,159)/t78-,79-,80-,81-,82-,83+,84+,92-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,118-,119-,120-,121-,122-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.30n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells

Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))		BDBM50273765
PNG
((4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,40S)-4-...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCC(=O)NCCCC[C@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O |r,wU:122.124,108.115,100.102,130.134,85.86,133.137,71.76,61.64,43.52,26.31,18.18,147.150,8.7,2.2,164.167,180.184,202.208,wD:117.119,89.98,79.82,67.68,55.58,35.39,142.145,152.155,4.4,175.180,194.200,209.215,222.228,(75.29,-8.17,;75.29,-6.62,;76.63,-5.85,;77.96,-6.62,;76.63,-4.32,;75.29,-3.55,;73.95,-4.32,;73.95,-5.86,;72.63,-3.55,;72.63,-2.01,;73.95,-1.24,;73.95,.31,;75.29,1.07,;72.62,1.08,;59.28,1.06,;57.95,.28,;57.95,-1.26,;56.62,-2.03,;56.62,-3.57,;55.28,-4.34,;53.95,-3.58,;53.95,-2.03,;52.61,-4.35,;51.28,-3.58,;49.95,-4.35,;49.95,-5.89,;48.61,-3.58,;48.61,-2.04,;49.95,-1.27,;49.95,.27,;48.61,1.04,;51.28,1.04,;47.27,-4.36,;45.95,-3.58,;45.95,-2.04,;44.61,-4.35,;44.61,-5.89,;45.95,-6.66,;45.95,-8.2,;47.28,-5.89,;43.27,-3.59,;41.94,-4.36,;41.94,-5.9,;40.61,-3.59,;40.61,-2.05,;41.94,-1.28,;43.27,-2.05,;44.6,-1.27,;44.6,.27,;45.93,1.04,;43.26,1.03,;41.94,.26,;39.27,-4.36,;37.94,-3.59,;37.94,-2.05,;36.61,-4.37,;36.61,-5.91,;37.94,-6.68,;35.27,-3.6,;33.94,-4.37,;33.94,-5.9,;32.61,-3.6,;32.61,-2.06,;33.94,-1.29,;31.27,-4.37,;29.94,-3.61,;29.94,-2.06,;28.6,-4.38,;27.27,-3.61,;25.94,-4.38,;25.94,-5.92,;24.6,-3.61,;24.6,-2.07,;25.94,-1.3,;27.26,-2.07,;25.94,.24,;23.26,-4.39,;21.94,-3.61,;21.94,-2.07,;20.6,-4.38,;20.6,-5.92,;21.94,-6.69,;19.26,-3.62,;17.93,-4.39,;17.93,-5.93,;16.6,-3.62,;15.26,-4.39,;13.93,-3.62,;13.93,-2.08,;12.59,-4.4,;12.59,-5.94,;13.93,-6.71,;15.27,-5.93,;16.59,-6.7,;16.6,-8.23,;15.26,-9.01,;13.93,-8.24,;11.26,-3.63,;9.93,-4.4,;9.93,-5.93,;8.59,-3.63,;7.26,-4.4,;5.93,-3.64,;5.93,-2.09,;4.59,-4.41,;3.26,-3.64,;1.92,-4.41,;1.92,-5.95,;.59,-3.64,;.59,-2.1,;1.92,-1.33,;1.92,.21,;.58,.98,;3.26,.98,;-.74,-4.42,;-2.07,-3.64,;-2.07,-2.1,;-3.41,-4.41,;-3.41,-5.95,;-4.75,-3.65,;-6.08,-4.41,;-6.08,-5.96,;-7.42,-3.65,;-8.75,-4.41,;-7.42,-2.11,;-6.08,-1.34,;-4.68,-1.96,;-3.65,-.81,;-4.42,.51,;-5.92,.19,;8.59,-2.09,;7.26,-1.31,;9.93,-1.32,;16.6,-2.08,;15.26,-1.31,;17.93,-1.31,;28.6,-5.91,;29.94,-6.68,;27.27,-6.68,;57.95,-4.34,;57.95,-5.87,;59.29,-3.57,;60.62,-4.34,;60.62,-5.88,;61.95,-3.56,;61.95,-2.02,;63.28,-4.33,;64.62,-3.56,;64.62,-2.02,;65.95,-4.33,;65.95,-5.87,;67.29,-3.56,;68.62,-4.32,;68.62,-5.86,;69.95,-6.63,;69.95,-8.17,;71.29,-8.95,;71.29,-10.48,;69.95,-3.55,;69.95,-2.01,;71.29,-4.33,;77.96,-3.55,;77.96,-2,;79.29,-4.31,;80.63,-3.54,;80.63,-1.99,;81.96,-1.23,;83.29,-1.99,;84.62,-1.23,;84.62,.31,;83.28,1.08,;81.96,.31,;81.96,-4.31,;81.96,-5.84,;83.3,-3.54,;84.63,-4.31,;84.63,-5.84,;85.96,-3.53,;85.96,-1.99,;87.3,-4.3,;88.63,-3.53,;88.63,-1.99,;89.96,-1.22,;91.37,-1.84,;92.39,-.69,;91.62,.63,;92.1,2.1,;91.07,3.24,;89.56,2.91,;89.09,1.45,;90.12,.31,;89.96,-4.3,;89.96,-5.84,;91.3,-3.53,;92.63,-4.3,;92.63,-5.83,;93.97,-6.6,;93.97,-8.14,;95.31,-5.83,;93.97,-3.52,;93.97,-1.98,;95.3,-4.3,;96.63,-3.53,;96.63,-1.98,;97.97,-1.21,;95.3,-1.21,;97.97,-4.29,;97.97,-5.83,;99.3,-3.52,;100.63,-4.29,;100.63,-5.82,;101.97,-6.59,;101.97,-8.13,;103.31,-8.9,;103.31,-10.44,;101.97,-3.52,;101.97,-1.98,;103.3,-4.28,;104.63,-3.51,;105.97,-4.28,;105.97,-5.82,;107.31,-3.51,;108.63,-4.28,;108.63,-5.82,;109.98,-6.59,;109.98,-8.12,;111.31,-8.89,;111.31,-10.43,;109.98,-11.2,;112.65,-11.2,;109.98,-3.51,;111.31,-4.27,;109.98,-1.96,)|
Show InChI InChI=1S/C150H228N40O43/c1-17-78(10)120(147(231)181-103(59-85-33-20-18-21-34-85)135(219)168-82(14)127(211)176-106(62-88-65-160-93-38-25-24-37-91(88)93)138(222)178-102(58-75(4)5)139(223)187-118(76(6)7)145(229)175-95(39-26-29-53-151)129(213)161-67-112(198)169-94(123(154)207)42-32-56-159-150(155)156)189-134(218)100-47-50-111(197)158-55-31-28-41-96(132(216)167-79(11)124(208)165-80(12)125(209)171-97(133(217)174-100)40-27-30-54-152)170-113(199)68-162-131(215)99(49-52-116(203)204)173-136(220)101(57-74(2)3)177-137(221)104(61-87-43-45-90(196)46-44-87)179-142(226)108(70-191)183-144(228)110(72-193)184-146(230)119(77(8)9)188-141(225)107(64-117(205)206)180-143(227)109(71-192)185-149(233)122(84(16)195)190-140(224)105(60-86-35-22-19-23-36-86)182-148(232)121(83(15)194)186-114(200)69-163-130(214)98(48-51-115(201)202)172-126(210)81(13)166-128(212)92(153)63-89-66-157-73-164-89/h18-25,33-38,43-46,65-66,73-84,92,94-110,118-122,160,191-196H,17,26-32,39-42,47-64,67-72,151-153H2,1-16H3,(H2,154,207)(H,157,164)(H,158,197)(H,161,213)(H,162,215)(H,163,214)(H,165,208)(H,166,212)(H,167,216)(H,168,219)(H,169,198)(H,170,199)(H,171,209)(H,172,210)(H,173,220)(H,174,217)(H,175,229)(H,176,211)(H,177,221)(H,178,222)(H,179,226)(H,180,227)(H,181,231)(H,182,232)(H,183,228)(H,184,230)(H,185,233)(H,186,200)(H,187,223)(H,188,225)(H,189,218)(H,190,224)(H,201,202)(H,203,204)(H,205,206)(H4,155,156,159)/t78-,79-,80-,81-,82-,83+,84+,92-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,118-,119-,120-,121-,122-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.30n/an/an/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Displacement of [125I]exendin(9-39) from human GLP1R expressed in HEK293 cells

Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1)


(Homo sapiens (Human))		BDBM50273765
PNG
((4S,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,40S)-4-...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H]1CCC(=O)NCCCC[C@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(N)=O |r,wU:122.124,108.115,100.102,130.134,85.86,133.137,71.76,61.64,43.52,26.31,18.18,147.150,8.7,2.2,164.167,180.184,202.208,wD:117.119,89.98,79.82,67.68,55.58,35.39,142.145,152.155,4.4,175.180,194.200,209.215,222.228,(75.29,-8.17,;75.29,-6.62,;76.63,-5.85,;77.96,-6.62,;76.63,-4.32,;75.29,-3.55,;73.95,-4.32,;73.95,-5.86,;72.63,-3.55,;72.63,-2.01,;73.95,-1.24,;73.95,.31,;75.29,1.07,;72.62,1.08,;59.28,1.06,;57.95,.28,;57.95,-1.26,;56.62,-2.03,;56.62,-3.57,;55.28,-4.34,;53.95,-3.58,;53.95,-2.03,;52.61,-4.35,;51.28,-3.58,;49.95,-4.35,;49.95,-5.89,;48.61,-3.58,;48.61,-2.04,;49.95,-1.27,;49.95,.27,;48.61,1.04,;51.28,1.04,;47.27,-4.36,;45.95,-3.58,;45.95,-2.04,;44.61,-4.35,;44.61,-5.89,;45.95,-6.66,;45.95,-8.2,;47.28,-5.89,;43.27,-3.59,;41.94,-4.36,;41.94,-5.9,;40.61,-3.59,;40.61,-2.05,;41.94,-1.28,;43.27,-2.05,;44.6,-1.27,;44.6,.27,;45.93,1.04,;43.26,1.03,;41.94,.26,;39.27,-4.36,;37.94,-3.59,;37.94,-2.05,;36.61,-4.37,;36.61,-5.91,;37.94,-6.68,;35.27,-3.6,;33.94,-4.37,;33.94,-5.9,;32.61,-3.6,;32.61,-2.06,;33.94,-1.29,;31.27,-4.37,;29.94,-3.61,;29.94,-2.06,;28.6,-4.38,;27.27,-3.61,;25.94,-4.38,;25.94,-5.92,;24.6,-3.61,;24.6,-2.07,;25.94,-1.3,;27.26,-2.07,;25.94,.24,;23.26,-4.39,;21.94,-3.61,;21.94,-2.07,;20.6,-4.38,;20.6,-5.92,;21.94,-6.69,;19.26,-3.62,;17.93,-4.39,;17.93,-5.93,;16.6,-3.62,;15.26,-4.39,;13.93,-3.62,;13.93,-2.08,;12.59,-4.4,;12.59,-5.94,;13.93,-6.71,;15.27,-5.93,;16.59,-6.7,;16.6,-8.23,;15.26,-9.01,;13.93,-8.24,;11.26,-3.63,;9.93,-4.4,;9.93,-5.93,;8.59,-3.63,;7.26,-4.4,;5.93,-3.64,;5.93,-2.09,;4.59,-4.41,;3.26,-3.64,;1.92,-4.41,;1.92,-5.95,;.59,-3.64,;.59,-2.1,;1.92,-1.33,;1.92,.21,;.58,.98,;3.26,.98,;-.74,-4.42,;-2.07,-3.64,;-2.07,-2.1,;-3.41,-4.41,;-3.41,-5.95,;-4.75,-3.65,;-6.08,-4.41,;-6.08,-5.96,;-7.42,-3.65,;-8.75,-4.41,;-7.42,-2.11,;-6.08,-1.34,;-4.68,-1.96,;-3.65,-.81,;-4.42,.51,;-5.92,.19,;8.59,-2.09,;7.26,-1.31,;9.93,-1.32,;16.6,-2.08,;15.26,-1.31,;17.93,-1.31,;28.6,-5.91,;29.94,-6.68,;27.27,-6.68,;57.95,-4.34,;57.95,-5.87,;59.29,-3.57,;60.62,-4.34,;60.62,-5.88,;61.95,-3.56,;61.95,-2.02,;63.28,-4.33,;64.62,-3.56,;64.62,-2.02,;65.95,-4.33,;65.95,-5.87,;67.29,-3.56,;68.62,-4.32,;68.62,-5.86,;69.95,-6.63,;69.95,-8.17,;71.29,-8.95,;71.29,-10.48,;69.95,-3.55,;69.95,-2.01,;71.29,-4.33,;77.96,-3.55,;77.96,-2,;79.29,-4.31,;80.63,-3.54,;80.63,-1.99,;81.96,-1.23,;83.29,-1.99,;84.62,-1.23,;84.62,.31,;83.28,1.08,;81.96,.31,;81.96,-4.31,;81.96,-5.84,;83.3,-3.54,;84.63,-4.31,;84.63,-5.84,;85.96,-3.53,;85.96,-1.99,;87.3,-4.3,;88.63,-3.53,;88.63,-1.99,;89.96,-1.22,;91.37,-1.84,;92.39,-.69,;91.62,.63,;92.1,2.1,;91.07,3.24,;89.56,2.91,;89.09,1.45,;90.12,.31,;89.96,-4.3,;89.96,-5.84,;91.3,-3.53,;92.63,-4.3,;92.63,-5.83,;93.97,-6.6,;93.97,-8.14,;95.31,-5.83,;93.97,-3.52,;93.97,-1.98,;95.3,-4.3,;96.63,-3.53,;96.63,-1.98,;97.97,-1.21,;95.3,-1.21,;97.97,-4.29,;97.97,-5.83,;99.3,-3.52,;100.63,-4.29,;100.63,-5.82,;101.97,-6.59,;101.97,-8.13,;103.31,-8.9,;103.31,-10.44,;101.97,-3.52,;101.97,-1.98,;103.3,-4.28,;104.63,-3.51,;105.97,-4.28,;105.97,-5.82,;107.31,-3.51,;108.63,-4.28,;108.63,-5.82,;109.98,-6.59,;109.98,-8.12,;111.31,-8.89,;111.31,-10.43,;109.98,-11.2,;112.65,-11.2,;109.98,-3.51,;111.31,-4.27,;109.98,-1.96,)|
Show InChI InChI=1S/C150H228N40O43/c1-17-78(10)120(147(231)181-103(59-85-33-20-18-21-34-85)135(219)168-82(14)127(211)176-106(62-88-65-160-93-38-25-24-37-91(88)93)138(222)178-102(58-75(4)5)139(223)187-118(76(6)7)145(229)175-95(39-26-29-53-151)129(213)161-67-112(198)169-94(123(154)207)42-32-56-159-150(155)156)189-134(218)100-47-50-111(197)158-55-31-28-41-96(132(216)167-79(11)124(208)165-80(12)125(209)171-97(133(217)174-100)40-27-30-54-152)170-113(199)68-162-131(215)99(49-52-116(203)204)173-136(220)101(57-74(2)3)177-137(221)104(61-87-43-45-90(196)46-44-87)179-142(226)108(70-191)183-144(228)110(72-193)184-146(230)119(77(8)9)188-141(225)107(64-117(205)206)180-143(227)109(71-192)185-149(233)122(84(16)195)190-140(224)105(60-86-35-22-19-23-36-86)182-148(232)121(83(15)194)186-114(200)69-163-130(214)98(48-51-115(201)202)172-126(210)81(13)166-128(212)92(153)63-89-66-157-73-164-89/h18-25,33-38,43-46,65-66,73-84,92,94-110,118-122,160,191-196H,17,26-32,39-42,47-64,67-72,151-153H2,1-16H3,(H2,154,207)(H,157,164)(H,158,197)(H,161,213)(H,162,215)(H,163,214)(H,165,208)(H,166,212)(H,167,216)(H,168,219)(H,169,198)(H,170,199)(H,171,209)(H,172,210)(H,173,220)(H,174,217)(H,175,229)(H,176,211)(H,177,221)(H,178,222)(H,179,226)(H,180,227)(H,181,231)(H,182,232)(H,183,228)(H,184,230)(H,185,233)(H,186,200)(H,187,223)(H,188,225)(H,189,218)(H,190,224)(H,201,202)(H,203,204)(H,205,206)(H4,155,156,159)/t78-,79-,80-,81-,82-,83+,84+,92-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,118-,119-,120-,121-,122-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 0.00288n/an/an/an/a



University of Texas at Dallas

Curated by ChEMBL


Assay Description
Activation of human GLP1R expressed in HEK293 cells assessed as effect on cAMP responsive element promoter driven luciferase expression

Bioorg Med Chem 16: 10106-12 (2008)


Article DOI: 10.1016/j.bmc.2008.10.006
BindingDB Entry DOI: 10.7270/Q2B857ZT
More data for this
Ligand-Target Pair