BDBM50274022 3-(5-(3-bromobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)-N-(3-hydroxyphenyl)propanamide::CHEMBL457233

SMILES: Oc1cccc(NC(=O)CCN2C(=S)S\C(=C/c3cccc(Br)c3)C2=O)c1

InChI Key: InChIKey=XKHYENLXUFEHRD-YBEGLDIGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274022   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-dependent RNA helicase DDX3X (Homo sapiens (Human))	BDBM50274022 (3-(5-(3-bromobenzylidene)-4-oxo-2-thioxothiazolidi...) Show SMILES Oc1cccc(NC(=O)CCN2C(=S)S\C(=C/c3cccc(Br)c3)C2=O)c1 Show InChI InChI=1S/C19H15BrN2O3S2/c20-13-4-1-3-12(9-13)10-16-18(25)22(19(26)27-16)8-7-17(24)21-14-5-2-6-15(23)11-14/h1-6,9-11,23H,7-8H2,(H,21,24)/b16-10-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Genetica Molecolare Curated by ChEMBL					Assay Description Inhibition of ATPase activity in human recombinant DDX3 expressed in Escherichia coli by luciferase-based luminescence assay in presence of ATP				J Med Chem 51: 6635-8 (2008) Article DOI: 10.1021/jm8008844 BindingDB Entry DOI: 10.7270/Q2XD11J3
					More data for this Ligand-Target Pair