BDBM50274140 1-methyl-2-(((1R,5S)-6-((4-(trifluoromethyl)phenoxy)methyl)-3-aza-bicyclo[3.1.0]hexan-3-yl)methyl)-1H-imidazo[4,5-c]pyridine::CHEMBL519817

SMILES: Cn1c(CN2C[C@H]3C(COc4ccc(cc4)C(F)(F)F)[C@H]3C2)nc2cnccc12

InChI Key: InChIKey=VATWUHJOCAJJQN-SJPCQFCGSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274140   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50274140 (1-methyl-2-(((1R,5S)-6-((4-(trifluoromethyl)phenox...) Show SMILES Cn1c(CN2C[C@H]3C(COc4ccc(cc4)C(F)(F)F)[C@H]3C2)nc2cnccc12 |r| Show InChI InChI=1S/C21H21F3N4O/c1-27-19-6-7-25-8-18(19)26-20(27)11-28-9-15-16(10-28)17(15)12-29-14-4-2-13(3-5-14)21(22,23)24/h2-8,15-17H,9-12H2,1H3/t15-,16+,17?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	251	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Activity at rat mGluR2 receptor expressed in HEK cells by FLIPR assay in presence of glutamate				Bioorg Med Chem Lett 18: 5493-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.026 BindingDB Entry DOI: 10.7270/Q2P26XZH
					More data for this Ligand-Target Pair